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News 
Events 
Section 2 
FAQ 
Integrated Supportive Care 
What is one:carepath?  
Who is One:carepath for? 
Patient Symptoms 
About You & Your Health Conditions 
Managing Your Health Condition 
Your Shared Care Plan 
Your Advance Care Planning 
Patient Portal Home Page 
Provider Pathway Content 
Diease Area Description 
Confirm Comorbidities 
Hero 
Quick Access 
Posters 
Call to Action 
Highlighted Features 
Footer 
Navbar 
Integrated Supportive Care 
Home 
Interactive Clinical Assessment 
Patients 
Content 
Symptom 
Fatigue 
STEP 1: IDENTIFY AND TREAT POTENTIAL REVERSIBLE CAUSES 
Disease Area (KF) 
Anxiety/Depression 
Breathlessness 
Constipation 
Edema 
Kidney 
COPD 
Heart 
Liver 
Cancer 
Fatigue 
New General Symptom Management Content - Symptom 1 
New Section 
Cause 1 
Edema 
Step 1. General Symptom Management  
New Section 
Cause 1 
Step 4. Palliative Care Consult  
Fatigue 
New General Symptom Management Content - Symptom 1 
New Section 
Cause 1 
Anxiety/Depression 
Step 1: General Symptom Management 
New Section 
Cause 1 
STEP 2: GENERAL Non-Pharmacological  
Non-Pharmacological Symptom Nuances 
Non-Pharmacological: Disease Specific Symptom Management  
Cause 1 
STEP 3: Pharmacological 
Liver Nuance 
Kidney Nuance 
Step 4: Palliative Care Consult 
Constipation old 
STEP 2: Non-Pharmacological Management 
STEP 3: Pharmacological Management 
STEP 4: Palliative Care Consult 
STEP 2: NON-PHARMACOLOGICAL MANAGEMENT	 
STEP 3: PHARMACOLOGICAL MANAGEMENT 
HEART FAILURE 
CIRRHOSIS  
KIDNEY FAILURE 
ABOUT PAIN: GENERAL DESCRIPTION & DEFINITION	 
STEP 1: IDENTIFY AND TREAT POTENTIAL REVERSIBLE CAUSES 
STEP 2: NON-PHARMACOLOGICAL MANAGEMENT	 
STEP 3: PHARMACOLOGICAL MANAGEMENT 
KIDNEY DISEASE - NEUROPATHIC 
KIDNEY DISEASE - NOCICEPTIVE 
STEP 4: PALLIATIVE CARE CONSULT 
PHARMACOLOGICAL PALLIATIVE CARE END OF LIFE NEUROPATHIC PAIN 
PHARMACOLOGICAL PALLIATIVE CARE END OF LIFE NOCICEPTIVE PAIN   
Superficial pain 
Bone  
Soft Tissue 
Muscle Relaxants 
Visceral 
Dexamethasone  
Bisphosphonate – Clodronate 1600-2400 mg PO daily 
Denosumab 120 mg SC every 4 weeks 
STEP 4: PALLIATIVE CARE CONSULT Version 2 
NSAID (systemic) 
NSAID (topical) 
Diazepam 
Baclofen 
Tizanidine 
GFR 0-7 
GFR 8-15 
GFR 15-30 
GFR 30+ 
EFS Severe 
EFS Not Severe 
Other Assessment Tool 
EFS Severe 
EFS Not Severe 
EFS Severe 
EFS Not Severe 
Heart Failure 
FEV1 
FEV2 
EFS Severe 
EFS Not Severe 
Weight 
Another Tool 
New Measurement Level 
Test Disease Area 
Fatigue old 
STEP 1: Consider the Underlying Causes of Fatigue 
STEP 2: Non Pharmacological Management of Fatigue 
STEP 3: Pharmacological Management v1 - Modelled after Med Table 
STEP 4: Palliative Care Consult 
Nausea & Vomiting 
Step 1: Consider the Underlying Causes of Nausea & Vomiting 
Step 2: Non-Pharmacological Management 
STEP 4: Palliative Care Consult 
Step 3: Pharmacological Management  
Dexamethasone-Append-Cancer 
HF-Replace-Buproprion 
Step 3: Pharmacological Management v2 - Fewest Nodes - Better management 
Dexamethasone-Append-Cancer 
STEP 3: Pharmacological Management V3 - Will not work as this does not align with wholistic approach 
Heart Failure 
Cancer 
STEP 3: Pharmacological Management v4 - Most Nodes and Difficult to Manage 
Modafinil (Provigil) 
Methylphenidate (Ritalin) 
Bupropion 
Modafinil-<>HF 
Methyphenidate <> HF 
Modafinil-Cirrhosis-ReduceDose <> HF 
KIdney 
STEP 3: Pharmacological Management v5 - Using Hide 
Dexamethasone 
Reduce Dose-Cirrhosis - Need to create nuance to a nuance 
Modafinil 
Dexamethasone 
Methylphenidate (Ritalin) 
Reduce Dose Cirrhosis 
STEP 3: Pharmacological Management of Fatigue 
Bupropion 
Methyphenidate & Modafinil 
Continue with algorithm 
Dexamethasone 
Bisacodyl; Peristaltic stimulant 
Cancer Adjusted Dose 
Methyphenidate & Modafinil 
Rule-Hide when HF selected 
Bupropion  
Rule-Hide when Cirrhosis selected 
Psyllium (Metamucil) 
Polyethylene glycol (PEG 3350) (LAX-A-DAY); Osmotic laxative 
Lactulose or Sorbitol; Osmotic laxative 
Sennosides (SenekotÒ); Peristaltic stimulant  
Glycerin Suppository 
Sodium-phosphate enema (Fleet Enema) 
Magnesium citrate or hydroxide or sulfate (Epsom salt)  
Methylnaltexone (RelistorÒ); Peripherally acting μ-opioid receptor antagonists (PAMORAs) 
Kidney Disease Dose Adjustment 
Naloxegol (MovantikÒ); Peripherally acting μ-opioid receptor antagonists (PAMORAs) 
KidneyDiseaseDoseAdjustment 
CirrhosisChildPughCAvoidUse 
Prucalopride; Prokinetics 
KidneyDiseaseDoseAdjustment 
Manual Disimpaction; for severe constipation 
Cholestatic Pruritus  
Step 1: Consider the Underlying Causes of Pruritus 
Step 2: Non-pharmacological Management  
Good Skin Care and Moisturizers 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Is this terminal phase of life? yes 
Is this terminal phase of life?  no   
Topical Treatment 
Pramoxine 
Capsaicin 0.025% or 0.075% Ointment 
 Menthol, Camphor and Phenol are separate products that can be added to most creams, typically in the range of 0.3-1.0% 
 Gamma-Linolenic acid (GLA) 2.2% cream 
Systemic Treatment  
Doxepin 
CI 
Precaution 
Comment 
Cholestyramine 
Rifampin 
CI 
Precaution 
Liver Cirrhosis  
Naltrexone 
CI 
Precaution 
Comment 
Restless Legs 
Step 1: Consider the Underlying Causes of Restless Leg Syndrome 
Step 2: Consider Non-Pharmacological Management 
Step 3: Pharmacological Management 
Gabapentin 
Dose 
CKD Dose 
Liver Dose 
Pregabalin 
Pramipexole (Mirapex) 
Rotigotine (Neupro) 
CI 
Precaution 
Comment  
CKD, Liver  
Dose 
CKD 
CI 
Precaution 
Comment  
Dose 
CI 
Precaution 
Comment 
Dose 
CI 
Precaution 
Comment 
Ropinirole (Requip) 
Dose 
CI 
Precaution 
Comment 
Midazolam (Versed) 
Dose 
CKD,Cir,CAN,HF 
COPD 
CI 
Precaution 
Comment  
CKD,HF 
COPD 
Neuropathic Pain (OLD) 
Step 1: Consider the Underlying Causes of Neuropathic Pain 
Step 2: Non-Pharmacological Management of Neuropathic Pain 
Step 3: Pharmacological Management of Neuropathic Pain 
Step 4: Palliative Care Consult 
Non-Opioid Treatment 
Step 2: Non-Opioid 
Opioid Treatment 
Acetaminophen 
Dose 
CI 
Precaution 
Comment 
Diclofenac Gel 
Dose 
Comment 
Hydromorphone 
Dose 
CI 
Precaution 
Comment 
Fentanyl Transdermal Patch 
Dose 
CI 
Precaution 
Comment 
Methadone 
Dose 
CI 
Precaution 
Comment 
Nociceptive Pain (backup -Old) 
Step 1: Consider the Underlying Causes of Nociceptive Pain 
Step 2: Non-pharmacological Management of Nociceptive Pain 
Step 3: Pharmacological Management of Nociceptive Pain 
Step 4: Palliative Care Consult 
Non-opioids (for mild pain (typically >3/10) 
Step 2: Moderate Pain (4-6/10) 
Opioids 
Step 5: Patient Education & Self-Care 
Gabapentin 
Dose 
CI 
Comment 
Pregabalin 
Dose 
CI 
Precaution 
Comment 
Amitriptyline 
Dose 
CI 
Precaution 
Comment 
Acetaminophen 
Dose 
CI 
Precaution 
Comment 
Hydromorphone 
Dose 
CI 
Precaution 
Comment 
Fentanyl Transdermal Patch 
Dose 
CI 
Precaution 
Comment 
Methadone 
Dose 
CI 
Precaution 
Comment 
Step 5 Patient Education & Self Care 
Step 5: Patient Education and Self Care 
When is an opioid indicated? 
Precaution 
General 
General 
Fatigue 
Step 1: Consider the Underlying Causes of Fatigue 
Step 2: Non-pharmacological Management of Fatigue 
Step 3: Pharmacological Management of Fatigue 
Step 4: Palliative Care Consult 
General - Precaution 
Methyphenidate 
Dose 
CI 
Precaution 
HF 
Modafinil 
Dose 
CI 
Precaution 
HF 
Dexamethasone 
Dose 
CI 
Precaution 
Constipation 
Step 1: Consider the Underlying Causes of Constipation 
Step 2: Non-pharmacological Management of Constipation 
Step 3: Pharmacological Management of Constipation 
Step 4: Palliative Care Consult 
Psyllium Husk 
Dose 
CI 
Comment 
General 
Precaution 
Polyethylene Glycol (PEG 3350) 
Dose 
CI 
Precaution 
Comment 
Sennosides 
Dose 
CI 
Precaution 
Comment 
Bisacodyl 
Dose 
CI 
Precaution 
Comment 
Cancer 
Glycerin or Bisacodyl Suppository  
Dose 
CI 
Precaution 
Comment 
KF 
Sodium-phosphate Enema (Fleet Enema) 
Dose 
CI 
Precaution 
Magnesium citrate or hydroxide or sulfate (Epsom Salt) 
Dose 
Precaution 
Methylnaltexone 
Dose 
CI 
Precaution 
Comment 
KF 
Cirrhosis 
General  
Cirrhosis 
Secretagogues (Linaclotide) 
Prokinetics (Prucalopride) 
Liver Renal - Precaution 
General - CI 
General - CI 
General - P 
General - CI 
General - P 
General - CI 
General - P 
COPD - P 
Liver - CI 
General 
General 
Lactulose  
Dose 
CI 
Precaution 
Comment 
General 
General 
General 
General 
General 
General 
General 
General 
General 
Dose - CKD 
General - CI 
General - Precaution 
General - Precaution 
High Mineral Oil Enema 
Dose 
CI 
Precaution 
Comment 
General - PI 
General - CI 
Dose - CKD 
General - CI 
Ducolax Suppository 
Dose 
CI 
Precaution 
Comment 
General - CI 
General - Precaution 
Demo Medication 
Dose 
CI 
Precaution 
Comment 
Alarm When COPD 
Warning when Heart Failure 
Hide When Cirrhosis 
Replace When Kidney Disease 
Hide When Cancer 
Append When Cancer 
Demo Symptom 
Step 1: Consider the Underlying Causes of Demo Symptom 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
New Med 1 
Dose 
CI 
Precaution 
Comment 
General - CI 
General - Precaution 
CKD - Dose 
CKD - Dose 
General - CI 
General - precaution 
Comment - HF 
Amitriptyline 
Dose 
CI 
Precaution 
Comment 
General - CI 
General - precaution 
Liver - CI 
Acetominophen 
Dose 
CI 
Precaution 
Comment 
General - Precaution 
Cirrhosis - CI (HIDE) 
Liver - CI  
HIDE 
NOT HF  
General 
General 
General 
General 
General 
General 
HIDE Liver 
CI 
General 
Non-Opioid Treatment - Accordion  
General Information  
Reference Accordion 
References  
Opioid Treatment - Accordion  
Opioid Considerations  
Initiating Opioid Therapy 
Opioid Titration 
Helpful Links 
Pain - Neuropathic  
Step 1: Consider the Underlying Causes of Neuropathic Pain 
Step 2: Non-Pharmacological Management of Neuropathic Pain 
Step 3: Pharmacological Management of Neuropathic Pain 
Step 4: Palliative Care Consult 
Reference Accordion 
Helpful Links 
References  
2. Non-Opioid Therapy 
3. Opioid Therapy 
Hydromorphone 
Dose 
CI 
Precaution 
Comment 
Fentanyl Transdermal Patch 
Dose 
CI 
Precaution 
Comment 
Methadone 
Dose 
CI 
Precaution 
Comment 
Opioid Treatment - Accordion 
Opioid Considerations  
Initiating Opioid Therapy 
Opioid Titration 
Gabapentin 
Dose 
CI 
Precaution 
Comment 
Pregabalin 
Dose 
CI 
Precaution 
Comment 
Amitriptyline 
Dose 
CI 
Precaution 
Comment 
Acetaminophen 
Dose 
CI 
Precaution 
Comment 
Non-Opioid Treatment - Accordion  
General Information  
CKD - Dose 
General - Precaution 
CKD - Dose 
General - precaution 
Comment - kidney/liver 
General - CI 
General - precaution 
General - Precaution 
General 
General 
General 
Comment - HF 
CKD/Cirrhosis 
Special Considerations for Opioid Induced Constipation (OIC) 
Dose - Cirrhosis 
Peripherally acting μ-opioid receptor antagonists (PAMORAS) 
HF/CKD Hide 
Methadone (2) 
Diclofenac Gel 
Dose 
CI 
Precaution 
Comment 
Kidney/Cirrhosis 
Precaution - Kidney Failure 
Morphine (immediate release) 
Dose 
CI 
Precaution 
Comment 
General 
CI - Cirrhosis 
Buprenorphine 
Dose 
CI 
Precaution 
Comment 
Oxycodone 
Dose 
CI 
Precaution 
Comment 
Cirrhosis/Kidney 
CI - Cirrhosis 
Comment - Kidney/Liver 
Kidney CI 
Dose - Cirrhosis 
Comment - kidney/liver 
Precaution - HF 
Cirrhosis - dose 
General - comment 
CI - liver/hepatic encephalopathy 
Carbamazepine 
Dose 
CI 
Precaution 
Comment 
General - CI 
CI - Cirrhosis/HF 
General - Precaution 
Dose adjust - CKD/Cirrhosis 
General Comment 
Doxepin 
Dose 
CI 
Precaution 
Comment 
General - CI 
CI - HF/Cirrhosis 
General - CI 
1. Start with Adjuvant Therapy  
Pain - Nociceptive 
Step 1: Consider the Underlying Causes of Nociceptive Pain 
Step 2: Non-pharmacological Management of Nociceptive Pain 
Step 3: Pharmacological Management of Nociceptive Pain 
Step 4: Palliative Care Consult 
 First Line Therapy (Bulk Forming Laxatives) 
First Line Therapy (Osmotic Laxatives) 
 First Line Therapy (Stimulant Laxatives) 
Second Line Therapy (Suppositories) 
Third Line Therapy (Alternative Treatments) 
 Fourth Line Therapy (Special Considerations) - Specialist referral recommended 
Comment 
Contraindication 
Comment 
General 
Non-Opioid Therapy 
Acetaminophen 
Dose 
CI 
Precaution 
Comment 
Cirrhosis - CI (HIDE) 
Diclofenac Gel 
Dose 
CI 
Precaution 
Comment 
Non-Opioid Treatment - Accordion  
Opioid Therapy 
Hydromorphone 
Dose 
CI 
Precaution 
Comment 
Kidney/Cirrhosis 
Fentanyl Transdermal Patch 
Dose 
CI 
Precaution 
Comment 
Precaution - Kidney Failure 
Morphine (immediate release) 
Dose 
CI 
Precaution 
Comment 
CI - Cirrhosis 
Hide - Kidney 
Buprenorphine 
Dose 
CI 
Precaution 
Comment 
Oxycodone 
Dose 
CI 
Precaution 
Comment 
Cirrhosis/Kidney 
CI - Cirrhosis 
Comment - Kidney/Liver 
Methadone 
Dose 
CI 
Precaution 
Comment 
Opioid Treatment - Accordion 
Opioid Considerations  
Initiating Opioid Therapy 
Opioid Titration 
CI - Liver 
General - CI 
Disclaimer 
Anorexia 
Step 1: Consider the Underlying Causes of Anorexia 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Delirium 
Step 1: Consider the Underlying Causes of Delirium 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Depression 
Step 1: Consider the Underlying Causes of Depression 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Diarrhea 
Step 1: Consider the Underlying Causes of Diarrhea 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Edema 
Step 1: Consider the Underlying Causes of Edema 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Numbness/Tingling 
Step 1: Consider the Underlying Causes of Numbness & Tingling 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Shortness of Breath 
Step 1: Consider the Underlying Causes of Shortness of Breath 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Bupropion 
Dose 
CI 
Precaution 
Comment 
General 
General 
General  
General  
General  
General 
General  
General 
Sleep Disturbance 
Step 1: Consider the Underlying Causes of Sleep Disturbance 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Helpful Links 
End of Life Care 
Step 1: General Principles of End of Life Care 
Step 2: Non-pharmacological Management 
Step 3: Medical Management 
Step 4: Palliative Care Consult 
Pregabalin 
Dose 
CI 
Precaution 
Comment 
DEMO Symptom - Line of Treatment 
Step 1: Consider the Underlying Causes of DEMO Symptom - Line of Treatment 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Pregabalin (2) 
Dose 
CI 
Precaution 
Comment 
HIDE for kidney/liver 
Pregabalin (1) 
Dose 
CI 
Precaution 
Comment 
Kidney 
Liver 
Helpful Links 
References 
Med 2 
Dose 
CI 
Precaution 
Comment 
HF 
Hide HF 
How to use onecarepath 
Second Line Therapy (Stimulants) 
Bisacodyl 
Dose 
CI 
Precaution 
Comment 
Cancer - Dose 
General - CI 
General 
COPD Description 
Heart Failure Description 
Cirrhosis Description 
Advanced Chronic Kidney Disease Description 
Cancer Description 
Mild Symptoms: limited evidence exists for most medications 
test2 
Step 4: Palliative Care Specialist Consultation 
Terminal Care Considerations 
If pain persists add a non-opioid +/- adjuvant therapy 
If pain persists consider adding an opioid, +/- adjuvant, +/- non-opioid 
End of Life Care 
Melatonin 
Dose 
CI 
Precaution 
Comment 
Mirtazapine 
Dose 
CI 
Precaution 
Comment 
Trazodone 
Dose 
CI 
Comment 
Doxepin 
Dose 
Precaution 
Comment 
Moderate to severe symptoms 
Zopiclone 
Dose 
CI 
Precaution 
Comment 
Gabapentin 
Dose 
CI 
Precaution 
Comment 
Pregabalin 
Dose 
CI 
Precaution 
Comment 
Precaution - HF 
Dose Adjustment - CKD 
Dose Adjustment - Cirrhosis 
Comment - Kidney/Liver 
CI - Liver HE 
Dose adjust - Kidney 
Dose Adjust - Liver 
comment - kidney/liver 
Precaution 
General CI 
Fentanyl Transdermal Patch 
Liver - MasterHide 
Liver CI 
Acetaminophen 
Liver CI - MasterHide 
Pain - Neuropathic 
Pain - Nociceptive 
Restless Legs 
Constipation 
Dose 
CI 
Precaution 
Comment 
Dose 
CI 
Precaution 
Comment 
med 1 for step 7 
Dose 
CI 
Precaution 
Comment 
Fatigue 
Shortness of Breath 
Morphine  
Carbamazepine 
Liver Heart - MasterHide 
Kidney - MasterHide 
Liver CI 
Doxepin 
Dose 
CI 
Precaution 
Comment 
Liver Heart - MasterHide 
Acetaminophen 
Dose 
CI 
Precaution 
Comment 
Liver - MasterHide 
Fentanyl Transdermal Patch 
Dose 
CI 
Precaution 
Comment 
Liver-MasterHide 
Morphine 
Dose 
CI 
Precaution 
Comment 
Kidney - MasterHide 
Sodium-phosphate Enema (Fleet Enema) 
Dose 
CI 
Precaution 
Comment 
Kidney_Heart Failure - MasterHide 
Methylphenidate 
Dose 
CI 
Precaution 
Comment 
Modafinil 
Dose 
CI 
Precaution 
Comment 
Heart Failure - MasterHide 
Heart Failure - MasterHide 
Doxepin 
Dose 
CI 
Precaution 
Comment 
Heart Liver - MasterHide 
HF Liver - Hide 
Helpful Links 
References 
Helpful Links 
References 
Metoclopramide 
Dose 
CI 
Precaution 
Comment 
General 
Kidney precaution 
Kidney/Liver Dose 
General 
Domperidone 
Dose 
CI 
Precaution 
Comment 
Liver dose adjustment 
General 
Liver CI 
General 
Haloperidol 
Dose 
Precaution 
Kidney Dose 
Liver Dose 
General 
Kidney Precaution 
Contraindications 
Comment 
General 
Dimenhydrinate 
Dose 
CI 
Precaution 
Comment 
General 
General 
General 
Haloperidol 
Dose 
CI 
Precaution 
Comment 
General CI 
General 
Methotrimeprazine 
Liver-MasterHide 
Ondansetron 
Dose 
CI 
Precaution 
Comment 
Kidney Dose Adjustment 
Liver Dose Adjustment 
General  
Liver Precaution 
Olanzapine 
Dose 
CI 
Precaution 
Comment 
General 
Kidney CI 
General 
CINV treatment only 
Dose 
CI 
Precaution 
Comment 
Dexamethasone 
Dose 
CI 
Precaution 
Comment 
all conditions except cancer CI 
Dexamethasone 
Dose 
All conditions except cancer - MasterHide 
Precaution 
Comment 
Patient Pathway 
Provider Pathway 
Medication MasterHide 
Patient Pathway 
What is One:carepath 
Provider Resources 
Other 
FAQ 
About one:carepath 
Useful Links 
Useful Contacts 
Events & Newsletters 
Disclaimer & Privacy 
Quality Improvement 
Quality Improvement 
KPI's 
Glossary 
Choosing Supportive Care 
Provider Pathway 
Advance Care Planning 
Patient Symptom Guidelines 
Patient Handouts 
About the Provider Pathway 
Choosing Supportive Care 
Dose 1 
Confirm Comorbidities and Risk Stratify 
Engage Specialty Care 
Education Materials 
Patient Resources 
For Healthcare Providers 
For Patient 
Access to Tools & Best Practice Supports 
Symptom & Medical Management 
Prepare for Care Planning With Your Healthcare Providers 
Better Understand Your Health Conditions 
Healthcare Providers 
Patients/Family 
Prepare for Conversations About Your Wishes & Needs 
Manage Your Health Conditions 
Action Plans 
Provider Checklists 
Clinical Pathways 
Complimentary Treatments 
Helpful Links 
References 
Lidocaine 2.5% cream 
Gabapentin 
Dose 
CI 
Precaution 
Comment 
CI Cirrhosis 
Renal + Liver Precaution 
Pregabalin 
Dose 
Comment 
ESKD Dose Adjust 
ESKD Dose Adjust 
Hide (cirrhosis med only) 
CI 
Precaution 
Comment 
Cirrhosis CI 
CI 
Precaution 
General Precaution 
Comment 
general Comment 
Liver - CI 
General - CI 
General 
General 
Renal 
Not indicated except for liver 
Renal 
CI 
General 
Renal 
Renal 
General 
General 
Renal Dose 
COPD Dose 
General 
General 
Liver Dose 
Cirrhosis Dose 
CI 
Liver + Renal CI 
Precautions 
Liver + Renal 
Dose 
Renal + Liver CI 
Liver + Renal Precaution 
Liver CI 
Cirrhosis precaution 
hide for non liver or kidney 
hide for non liver or kidney 
hide for non-liver or kidney 
Helpful Links 
References 
Liver CI 
HF Precaution 
General 
Liver Dose 
General 
Liver CI 
CKD, Liver 
Ascites 
Step 1: Initial Workup 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Hepatic Encephalopathy 
Step 1: Consider the Underlying Causes of Hepatic Encephalopathy 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Hepatocellular Carcinoma 
Step 1: Consider the Underlying Causes of Hepatocellular Carcinoma 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
What is Worrying you right now? 
Your Health Conditions 
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Your Wishes and Preferences 
Symptom Management Guides  
Your Health Plan 
What is Shared Care Planning? 
Steps in Shared Care Planning 
What is Advance Care Planning? 
Your Green Sleeve 
Preparing for the Final Weeks & Days of Life 
Your Shared Care Plan 
Basic fluid workup (for patients who have had a thorough fluid analysis before): 
Extended ascites fluid workup (for patient having a first-tine paracentesis):  
Mild Ascites 
Spironolactone Monotherapy 
Dose 
CI 
Precaution 
Comment 
General Precaution 
Amiloride (Substitute for Spironolactone) 
Dose 
CI 
Precaution 
Comment 
Mild to Moderate Ascites 
Tense Ascites 
Lactulose (oral) 
Dose 
CI 
Precaution 
Comment 
If oral intake safe/tolerated 
If oral intake not safe/not tolerated 
Lactulose (nasogastric) 
If improvement start secondary prophylaxis 
Secondary Prophylaxis 
Dose 
CI 
Precaution 
Comment 
If no improvement 
Rifaximin 
Dose 
CI 
Precaution 
Comment 
Patient Symptom - Pain 
Step 1: Consider the Underlying Causes of Patient Symptom - Pain 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Patient Symptom - Pain 
Step 1: What can I try at home? 
Step 2: What treatment choices do I have? 
Step 3: Pharmacological Management 
Step 4: Pain Resources 
Tailored Outputs Based on Conditions 
Confirm Comorbidities 
End Of Life Guideline 
End of Life 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
CKD Associated Pruritus  
Step 1: Consider the Underlying Causes of CKD Associated Pruritus  
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Good Skin Care 
Complimentary Treatments 
Topical Treatment 
Systemic Treatment 
Pramoxine 
Dose 
CI 
Precaution 
Comment 
Capsaicin 0.025% or 0.075% Ointment 
Dose 
CI 
Precaution 
Comment 
Menthol, Camphor and Phenol are separate products that can be added to most creams, typically in the range of 0.3-1.0% 
Dose 
CI 
Precaution 
Comment 
 Gamma-Linolenic acid (GLA) 2.2% cream 
Dose 
CI 
Precaution 
Comment 
Lidocaine 2.5% cream 
Dose 
CI 
Precaution 
Comment 
Dose 
CI 
Precaution 
Comment 
Pregabalin 
Dose 
CI 
Precaution 
Comment 
Gabapentin 
Dose 
CI 
Precaution 
Comment 
ESKD Dose Adjustment 
Cirrhosis Dose 
Liver & Renal CI 
Liver & Renal  
ESKD Dose 
Liver Dose 
Risk Staging 
Self-Management & Lifestyle Modifications: General  
Establish Community Support & Referrals 
Advance Care Planning 
Palliative Care 
Final Weeks and Days of Life 
COPD 
Heart Failure 
Cirrhosis  
Advanced CKD 
Cancer  
COPD  
Heart Failure  
Cirrhosis  
Advanced CKD 
Cancer  
COPD 
Heart Failure 
Cirrhosis 
Advanced CKD 
Cancer 
COPD 
Heart Failure 
Cirrhosis 
Advanced CKD 
Cancer 
COPD 
Heart Failure 
Cirrhosis 
Advanced CKD 
Cancer 
Message 
COPD 
Heart Failure 
Cirrhosis 
Advanced CKD 
Cancer 
Dosing for Combination Diuretics 
Dose 
CI 
Precaution 
Comment 
Large-volume (≥ 5L) paracentesis AND start combination diuretics if no contraindications 
Dose 
CI 
Precaution 
Comment 
Diagnostic Criteria for Refractory Ascites & Management 
Monitoring for Patients on Diuretics 
How to titrate up diuretics 
References 
Additional Resources 
COPD  
Step 1: COPD Management 
Step 2: Pharmacological Management 
Heart Failure Management 
Step 1: Consider the Underlying Causes of Heart Failure Management 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 3: Exacerbation Management 
Dose 
CI 
Precaution 
Comment 
Dose 
CI 
Precaution 
Comment 
Examples of converting oral to subcutaneous administration 
When to Consult a Palliative Care Specialist 
EMS Palliative and End of Life Care Assess, Treat, and Refer (EMS PEOLC ATR) Initiative 
Services required for caring for patients at home, location of care and location of death 
Step 5: What Happens After Death? 
Symptom Management Near the End of Life 
Pain  
Breathlessness 
Fluid Management 
Respiratory Secretions 
Constipation 
Fatigue & Sleep Disturbance 
Restless Legs Syndrome 
Delirium & Agitation  
Poor Appetite & Intake  
Muscle Cramps 
Helpful Links 
Shared Care Plan 
COPD 
Heart Failure 
Cirrhosis 
Advanced CKD 
Cancer 
Muscle Cramps 
Step 1: Consider the Underlying Causes of Muscle Cramps 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Symptom Management 
Medical Management 
General 
Smoking 
 Immunization 
 Nutrition 
 Exercise 
Social Determinants of Health 
 Home Care 
Advance Care Planning 
Salt Intake 
Fluid Intake  
Alcohol  
 Obesity Counselling 
Mood and Stress Management  
Resources 
Pulmonary Rehabilitation 
Calgary COPD and Asthma Program  (CCAP) 
Alberta Healthy Living Program  
Community Paramedics (CP) 
Home Care (COPD homecare specific teams) 
Alberta Quits  
Other Resources 
Your Support Team 
 Palliative & End of Life Care 
Symptom Management for Advanced CKD 
Constipation 
What causes constipation? 
What you can do to help manage your constipation 
When you should talk to your healthcare provider 
Medication 1 
Dose 
CI 
Precaution 
Comment 
Mona 
Step 1: Consider the Underlying Causes of Mona 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Medication 1 
Dose 
CI 
Precaution 
Comment 
CKD 
Acidosis Guideline 
Acidosis (Metabolic) - Clinical Algorithm  
Dosing Chart for Sodium Bicarbonate 
Additional Resources: 
Blood Pressure Guideline 
Additional Resources 
Sodium/Fluid Statement 
Sodium Intake 
Fluid Intake 
Rehydration if patients are not able to drink orally 
Considerations at End of Life 
Nausea & Vomiting 
Accordion Container 
What you can do to help manage nausea & vomiting? 
When you should talk to my healthcare team? 
Links 
Accordion Container 
Links 
Pain 
Accordion Container 
What you can do to help manage your pain 
When you should talk to your healthcare team 
Links 
Shortness of Breath 
Accordion Container 
What causes shortness of breath  
What you can do to help manage shortness of breath  
When you should talk to your healthcare team 
Links 
Anemia Guideline 
Iron Protocol for Conservatively Managed Patients 
HGB/ESA Protocol & Dose Adjustment Schedule for darbepoietin (Aranesp®) 
Additional Resources 
Calcium/Phosphorus Guideline 
Dose Adjustment Guideline for Phosphate Binders – Recommended Initial Calcium Dosing 
Dose Adjustment Guideline for Non-Calcium Based Phosphate Binders (may be used alone or as an adjuvant therapy) 
High Calcium Clinical Guideline 
Lipids Guideline 
Additional Resources 
Potassium Guideline 
Potassium - Clinical Algorithm  
Additional Resources 
Vitamin D Statement 
Considerations at End of Life: 
Additional Resources 
Calcitriol (active form of vitamin D, e.g. Rocaltrol) 
Glossary 
acc1 
acc item1 
fasdf 
p1 
replace  
Container 
Med1 
Dose 
CI 
Precaution 
Comment 
repalce when HF 
hide when cancer 
acc no 1 
Med 1 
Dose 
CI 
Precaution 
Comment 
replace when HF 
Hide when Cancer 
Shared Care Planning 
Supportive Care 
Health Condition 
Chronic Disease 
Preferences 
Health Plan 
Healthcare Team 
Advance Care Planning or ACP 
Personal Directive  
Enduring Power Attorney  
Goals of Care   (Designation) or GoC 
“Greensleeve”  
Palliative care 
End of Life Care 
Accordion Container 
Additional Resources 
What is Palliative Care? 
Accordion Container 
Darbepoetin starting dose when Hgb < 95 g/L and iron replete. 
Darbepoetin adjustment schedule if Hgb BELOW target: 
Darbepoetin adjustment schedule if Hgb ABOVE target or rising significantly: 
Dose Adjustment Schedule for epoetin alpha (Eprex ®) 
Glossary 
Symptom and Medical Management 
Patient Handouts 
Maintenance: Calcium Dosing Guideline 
Additional Resources 
What is End of Life Care? 
Helpful Links 
References 
Helpful Links 
References 
References 
Helpful Links 
References 
Additional Resources 
References 
Additional Resources 
References 
Additional Resources 
References 
Hide for non liver or kidney 
Not indicated except in liver 
Step 1: Continue Goals of Care Discussions 
References 
Hide for HF 
except HF 
General 
General 
General 
General 
General 
Restless Legs 
Lack of Appetite 
Depression & Anxiety 
Fatigue 
Muscle Cramps 
Numbness & Tingling 
Taste Changes 
Diarrhea 
Dehydration 
Itchiness 
Swelling 
Difficulty Swallowing 
Sleep Problems 
Palliative Care 
Accordion Container 
What causes restless leg syndrome 
What you can do to help manage your restless leg syndrome 
When you should talk to your healthcare team 
Accordion Container 
What causes a lack of appetite 
What you can do to help manage your lack of appetite 
When you should talk to your healthcare team 
Accordion container 
What causes depression & anxiety 
What you can do to help manage your depression & anxiety 
When you should talk to your healthcare team 
Accordion container 
What causes fatigue 
What you can do to help manage you fatigue 
When you should talk to your healthcare team 
Accordion container 
What causes muscle cramps 
What you can do to help manage your muscle cramps 
Accordion container 
When you should talk to your healthcare team 
What causes numbness & tingling 
What you can do to help manage your numbness & tingling 
When to talk to your healthcare team 
Accordion Container 
What causes taste changes? 
What you can do to help manage your taste changes 
When to talk to your healthcare team 
Accordion Container 
What causes diarrhea? 
What you can do to help manage your diarrhea 
When to talk to your healthcare team 
Accordion Container 
What causes dehydration? 
What you can do to help manage your dehydration 
When to talk to your healthcare team 
Accordion Container 
What causes itchiness? 
What you can do to help manage your itchiness 
When to talk to your healthcare team 
Accordion Container 
What causes swelling? 
What you can do to help manage your swelling 
When to talk to your healthcare team 
Accordion Container 
What causes sleep problems? 
What you can do to help manage your sleep problems 
When to talk to your healthcare team 
What causes nausea & vomiting? 
Accordion Container 
What you can do to help manage your difficulty with swallowing 
When to talk to your healthcare team 
What causes difficulty in swallowing? 
What causes nausea & Vomiting 
What causes pain 
Accordion Container 
what can I expect in the last weeks and days of life? 
What will happen if my family & friends can't care for me at home? 
Helpful links to learn more about palliative and end of life care in Alberta 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Cancer Management 
Step 1: Consider the Underlying Causes of Cancer Management 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Advance Care Planning 
Palliative & End of Life 
Access to Resources 
Topical Compounded Products 
Dose 
CI 
Precaution 
Comment 
Caution 
General-Caution 
Topical Compounded Products 
Dose 
CI 
Precaution 
Comment 
General Condition 
condition for HF & KD 
General CI 
Additional Resources 
Lemborexant 
Dose 
CI 
Precaution 
Comment 
Hide for Kidney and Cirrhosis 
Hide for Cancer COPD HF 
Sertraline 
Dose 
CI 
Precaution 
Comment 
CI-Genernal 
General 
CI for Cirrhosis 
Living with Heart Failure 
Living with COPD 
Additional Resources 
                    
                        TargetSectionId 
                        Section 1 
News 
Events 
Section 2 
FAQ 
Integrated Supportive Care 
What is one:carepath?  
Who is One:carepath for? 
Patient Symptoms 
About You & Your Health Conditions 
Managing Your Health Condition 
Your Shared Care Plan 
Your Advance Care Planning 
Patient Portal Home Page 
Provider Pathway Content 
Diease Area Description 
Confirm Comorbidities 
Hero 
Quick Access 
Posters 
Call to Action 
Highlighted Features 
Footer 
Navbar 
Integrated Supportive Care 
Home 
Interactive Clinical Assessment 
Patients 
Content 
Symptom 
Fatigue 
STEP 1: IDENTIFY AND TREAT POTENTIAL REVERSIBLE CAUSES 
Disease Area (KF) 
Anxiety/Depression 
Breathlessness 
Constipation 
Edema 
Kidney 
COPD 
Heart 
Liver 
Cancer 
Fatigue 
New General Symptom Management Content - Symptom 1 
New Section 
Cause 1 
Edema 
Step 1. General Symptom Management  
New Section 
Cause 1 
Step 4. Palliative Care Consult  
Fatigue 
New General Symptom Management Content - Symptom 1 
New Section 
Cause 1 
Anxiety/Depression 
Step 1: General Symptom Management 
New Section 
Cause 1 
STEP 2: GENERAL Non-Pharmacological  
Non-Pharmacological Symptom Nuances 
Non-Pharmacological: Disease Specific Symptom Management  
Cause 1 
STEP 3: Pharmacological 
Liver Nuance 
Kidney Nuance 
Step 4: Palliative Care Consult 
Constipation old 
STEP 2: Non-Pharmacological Management 
STEP 3: Pharmacological Management 
STEP 4: Palliative Care Consult 
STEP 2: NON-PHARMACOLOGICAL MANAGEMENT	 
STEP 3: PHARMACOLOGICAL MANAGEMENT 
HEART FAILURE 
CIRRHOSIS  
KIDNEY FAILURE 
ABOUT PAIN: GENERAL DESCRIPTION & DEFINITION	 
STEP 1: IDENTIFY AND TREAT POTENTIAL REVERSIBLE CAUSES 
STEP 2: NON-PHARMACOLOGICAL MANAGEMENT	 
STEP 3: PHARMACOLOGICAL MANAGEMENT 
KIDNEY DISEASE - NEUROPATHIC 
KIDNEY DISEASE - NOCICEPTIVE 
STEP 4: PALLIATIVE CARE CONSULT 
PHARMACOLOGICAL PALLIATIVE CARE END OF LIFE NEUROPATHIC PAIN 
PHARMACOLOGICAL PALLIATIVE CARE END OF LIFE NOCICEPTIVE PAIN   
Superficial pain 
Bone  
Soft Tissue 
Muscle Relaxants 
Visceral 
Dexamethasone  
Bisphosphonate – Clodronate 1600-2400 mg PO daily 
Denosumab 120 mg SC every 4 weeks 
STEP 4: PALLIATIVE CARE CONSULT Version 2 
NSAID (systemic) 
NSAID (topical) 
Diazepam 
Baclofen 
Tizanidine 
GFR 0-7 
GFR 8-15 
GFR 15-30 
GFR 30+ 
EFS Severe 
EFS Not Severe 
Other Assessment Tool 
EFS Severe 
EFS Not Severe 
EFS Severe 
EFS Not Severe 
Heart Failure 
FEV1 
FEV2 
EFS Severe 
EFS Not Severe 
Weight 
Another Tool 
New Measurement Level 
Test Disease Area 
Fatigue old 
STEP 1: Consider the Underlying Causes of Fatigue 
STEP 2: Non Pharmacological Management of Fatigue 
STEP 3: Pharmacological Management v1 - Modelled after Med Table 
STEP 4: Palliative Care Consult 
Nausea & Vomiting 
Step 1: Consider the Underlying Causes of Nausea & Vomiting 
Step 2: Non-Pharmacological Management 
STEP 4: Palliative Care Consult 
Step 3: Pharmacological Management  
Dexamethasone-Append-Cancer 
HF-Replace-Buproprion 
Step 3: Pharmacological Management v2 - Fewest Nodes - Better management 
Dexamethasone-Append-Cancer 
STEP 3: Pharmacological Management V3 - Will not work as this does not align with wholistic approach 
Heart Failure 
Cancer 
STEP 3: Pharmacological Management v4 - Most Nodes and Difficult to Manage 
Modafinil (Provigil) 
Methylphenidate (Ritalin) 
Bupropion 
Modafinil-<>HF 
Methyphenidate <> HF 
Modafinil-Cirrhosis-ReduceDose <> HF 
KIdney 
STEP 3: Pharmacological Management v5 - Using Hide 
Dexamethasone 
Reduce Dose-Cirrhosis - Need to create nuance to a nuance 
Modafinil 
Dexamethasone 
Methylphenidate (Ritalin) 
Reduce Dose Cirrhosis 
STEP 3: Pharmacological Management of Fatigue 
Bupropion 
Methyphenidate & Modafinil 
Continue with algorithm 
Dexamethasone 
Bisacodyl; Peristaltic stimulant 
Cancer Adjusted Dose 
Methyphenidate & Modafinil 
Rule-Hide when HF selected 
Bupropion  
Rule-Hide when Cirrhosis selected 
Psyllium (Metamucil) 
Polyethylene glycol (PEG 3350) (LAX-A-DAY); Osmotic laxative 
Lactulose or Sorbitol; Osmotic laxative 
Sennosides (SenekotÒ); Peristaltic stimulant  
Glycerin Suppository 
Sodium-phosphate enema (Fleet Enema) 
Magnesium citrate or hydroxide or sulfate (Epsom salt)  
Methylnaltexone (RelistorÒ); Peripherally acting μ-opioid receptor antagonists (PAMORAs) 
Kidney Disease Dose Adjustment 
Naloxegol (MovantikÒ); Peripherally acting μ-opioid receptor antagonists (PAMORAs) 
KidneyDiseaseDoseAdjustment 
CirrhosisChildPughCAvoidUse 
Prucalopride; Prokinetics 
KidneyDiseaseDoseAdjustment 
Manual Disimpaction; for severe constipation 
Cholestatic Pruritus  
Step 1: Consider the Underlying Causes of Pruritus 
Step 2: Non-pharmacological Management  
Good Skin Care and Moisturizers 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Is this terminal phase of life? yes 
Is this terminal phase of life?  no   
Topical Treatment 
Pramoxine 
Capsaicin 0.025% or 0.075% Ointment 
 Menthol, Camphor and Phenol are separate products that can be added to most creams, typically in the range of 0.3-1.0% 
 Gamma-Linolenic acid (GLA) 2.2% cream 
Systemic Treatment  
Doxepin 
CI 
Precaution 
Comment 
Cholestyramine 
Rifampin 
CI 
Precaution 
Liver Cirrhosis  
Naltrexone 
CI 
Precaution 
Comment 
Restless Legs 
Step 1: Consider the Underlying Causes of Restless Leg Syndrome 
Step 2: Consider Non-Pharmacological Management 
Step 3: Pharmacological Management 
Gabapentin 
Dose 
CKD Dose 
Liver Dose 
Pregabalin 
Pramipexole (Mirapex) 
Rotigotine (Neupro) 
CI 
Precaution 
Comment  
CKD, Liver  
Dose 
CKD 
CI 
Precaution 
Comment  
Dose 
CI 
Precaution 
Comment 
Dose 
CI 
Precaution 
Comment 
Ropinirole (Requip) 
Dose 
CI 
Precaution 
Comment 
Midazolam (Versed) 
Dose 
CKD,Cir,CAN,HF 
COPD 
CI 
Precaution 
Comment  
CKD,HF 
COPD 
Neuropathic Pain (OLD) 
Step 1: Consider the Underlying Causes of Neuropathic Pain 
Step 2: Non-Pharmacological Management of Neuropathic Pain 
Step 3: Pharmacological Management of Neuropathic Pain 
Step 4: Palliative Care Consult 
Non-Opioid Treatment 
Step 2: Non-Opioid 
Opioid Treatment 
Acetaminophen 
Dose 
CI 
Precaution 
Comment 
Diclofenac Gel 
Dose 
Comment 
Hydromorphone 
Dose 
CI 
Precaution 
Comment 
Fentanyl Transdermal Patch 
Dose 
CI 
Precaution 
Comment 
Methadone 
Dose 
CI 
Precaution 
Comment 
Nociceptive Pain (backup -Old) 
Step 1: Consider the Underlying Causes of Nociceptive Pain 
Step 2: Non-pharmacological Management of Nociceptive Pain 
Step 3: Pharmacological Management of Nociceptive Pain 
Step 4: Palliative Care Consult 
Non-opioids (for mild pain (typically >3/10) 
Step 2: Moderate Pain (4-6/10) 
Opioids 
Step 5: Patient Education & Self-Care 
Gabapentin 
Dose 
CI 
Comment 
Pregabalin 
Dose 
CI 
Precaution 
Comment 
Amitriptyline 
Dose 
CI 
Precaution 
Comment 
Acetaminophen 
Dose 
CI 
Precaution 
Comment 
Hydromorphone 
Dose 
CI 
Precaution 
Comment 
Fentanyl Transdermal Patch 
Dose 
CI 
Precaution 
Comment 
Methadone 
Dose 
CI 
Precaution 
Comment 
Step 5 Patient Education & Self Care 
Step 5: Patient Education and Self Care 
When is an opioid indicated? 
Precaution 
General 
General 
Fatigue 
Step 1: Consider the Underlying Causes of Fatigue 
Step 2: Non-pharmacological Management of Fatigue 
Step 3: Pharmacological Management of Fatigue 
Step 4: Palliative Care Consult 
General - Precaution 
Methyphenidate 
Dose 
CI 
Precaution 
HF 
Modafinil 
Dose 
CI 
Precaution 
HF 
Dexamethasone 
Dose 
CI 
Precaution 
Constipation 
Step 1: Consider the Underlying Causes of Constipation 
Step 2: Non-pharmacological Management of Constipation 
Step 3: Pharmacological Management of Constipation 
Step 4: Palliative Care Consult 
Psyllium Husk 
Dose 
CI 
Comment 
General 
Precaution 
Polyethylene Glycol (PEG 3350) 
Dose 
CI 
Precaution 
Comment 
Sennosides 
Dose 
CI 
Precaution 
Comment 
Bisacodyl 
Dose 
CI 
Precaution 
Comment 
Cancer 
Glycerin or Bisacodyl Suppository  
Dose 
CI 
Precaution 
Comment 
KF 
Sodium-phosphate Enema (Fleet Enema) 
Dose 
CI 
Precaution 
Magnesium citrate or hydroxide or sulfate (Epsom Salt) 
Dose 
Precaution 
Methylnaltexone 
Dose 
CI 
Precaution 
Comment 
KF 
Cirrhosis 
General  
Cirrhosis 
Secretagogues (Linaclotide) 
Prokinetics (Prucalopride) 
Liver Renal - Precaution 
General - CI 
General - CI 
General - P 
General - CI 
General - P 
General - CI 
General - P 
COPD - P 
Liver - CI 
General 
General 
Lactulose  
Dose 
CI 
Precaution 
Comment 
General 
General 
General 
General 
General 
General 
General 
General 
General 
Dose - CKD 
General - CI 
General - Precaution 
General - Precaution 
High Mineral Oil Enema 
Dose 
CI 
Precaution 
Comment 
General - PI 
General - CI 
Dose - CKD 
General - CI 
Ducolax Suppository 
Dose 
CI 
Precaution 
Comment 
General - CI 
General - Precaution 
Demo Medication 
Dose 
CI 
Precaution 
Comment 
Alarm When COPD 
Warning when Heart Failure 
Hide When Cirrhosis 
Replace When Kidney Disease 
Hide When Cancer 
Append When Cancer 
Demo Symptom 
Step 1: Consider the Underlying Causes of Demo Symptom 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
New Med 1 
Dose 
CI 
Precaution 
Comment 
General - CI 
General - Precaution 
CKD - Dose 
CKD - Dose 
General - CI 
General - precaution 
Comment - HF 
Amitriptyline 
Dose 
CI 
Precaution 
Comment 
General - CI 
General - precaution 
Liver - CI 
Acetominophen 
Dose 
CI 
Precaution 
Comment 
General - Precaution 
Cirrhosis - CI (HIDE) 
Liver - CI  
HIDE 
NOT HF  
General 
General 
General 
General 
General 
General 
HIDE Liver 
CI 
General 
Non-Opioid Treatment - Accordion  
General Information  
Reference Accordion 
References  
Opioid Treatment - Accordion  
Opioid Considerations  
Initiating Opioid Therapy 
Opioid Titration 
Helpful Links 
Pain - Neuropathic  
Step 1: Consider the Underlying Causes of Neuropathic Pain 
Step 2: Non-Pharmacological Management of Neuropathic Pain 
Step 3: Pharmacological Management of Neuropathic Pain 
Step 4: Palliative Care Consult 
Reference Accordion 
Helpful Links 
References  
2. Non-Opioid Therapy 
3. Opioid Therapy 
Hydromorphone 
Dose 
CI 
Precaution 
Comment 
Fentanyl Transdermal Patch 
Dose 
CI 
Precaution 
Comment 
Methadone 
Dose 
CI 
Precaution 
Comment 
Opioid Treatment - Accordion 
Opioid Considerations  
Initiating Opioid Therapy 
Opioid Titration 
Gabapentin 
Dose 
CI 
Precaution 
Comment 
Pregabalin 
Dose 
CI 
Precaution 
Comment 
Amitriptyline 
Dose 
CI 
Precaution 
Comment 
Acetaminophen 
Dose 
CI 
Precaution 
Comment 
Non-Opioid Treatment - Accordion  
General Information  
CKD - Dose 
General - Precaution 
CKD - Dose 
General - precaution 
Comment - kidney/liver 
General - CI 
General - precaution 
General - Precaution 
General 
General 
General 
Comment - HF 
CKD/Cirrhosis 
Special Considerations for Opioid Induced Constipation (OIC) 
Dose - Cirrhosis 
Peripherally acting μ-opioid receptor antagonists (PAMORAS) 
HF/CKD Hide 
Methadone (2) 
Diclofenac Gel 
Dose 
CI 
Precaution 
Comment 
Kidney/Cirrhosis 
Precaution - Kidney Failure 
Morphine (immediate release) 
Dose 
CI 
Precaution 
Comment 
General 
CI - Cirrhosis 
Buprenorphine 
Dose 
CI 
Precaution 
Comment 
Oxycodone 
Dose 
CI 
Precaution 
Comment 
Cirrhosis/Kidney 
CI - Cirrhosis 
Comment - Kidney/Liver 
Kidney CI 
Dose - Cirrhosis 
Comment - kidney/liver 
Precaution - HF 
Cirrhosis - dose 
General - comment 
CI - liver/hepatic encephalopathy 
Carbamazepine 
Dose 
CI 
Precaution 
Comment 
General - CI 
CI - Cirrhosis/HF 
General - Precaution 
Dose adjust - CKD/Cirrhosis 
General Comment 
Doxepin 
Dose 
CI 
Precaution 
Comment 
General - CI 
CI - HF/Cirrhosis 
General - CI 
1. Start with Adjuvant Therapy  
Pain - Nociceptive 
Step 1: Consider the Underlying Causes of Nociceptive Pain 
Step 2: Non-pharmacological Management of Nociceptive Pain 
Step 3: Pharmacological Management of Nociceptive Pain 
Step 4: Palliative Care Consult 
 First Line Therapy (Bulk Forming Laxatives) 
First Line Therapy (Osmotic Laxatives) 
 First Line Therapy (Stimulant Laxatives) 
Second Line Therapy (Suppositories) 
Third Line Therapy (Alternative Treatments) 
 Fourth Line Therapy (Special Considerations) - Specialist referral recommended 
Comment 
Contraindication 
Comment 
General 
Non-Opioid Therapy 
Acetaminophen 
Dose 
CI 
Precaution 
Comment 
Cirrhosis - CI (HIDE) 
Diclofenac Gel 
Dose 
CI 
Precaution 
Comment 
Non-Opioid Treatment - Accordion  
Opioid Therapy 
Hydromorphone 
Dose 
CI 
Precaution 
Comment 
Kidney/Cirrhosis 
Fentanyl Transdermal Patch 
Dose 
CI 
Precaution 
Comment 
Precaution - Kidney Failure 
Morphine (immediate release) 
Dose 
CI 
Precaution 
Comment 
CI - Cirrhosis 
Hide - Kidney 
Buprenorphine 
Dose 
CI 
Precaution 
Comment 
Oxycodone 
Dose 
CI 
Precaution 
Comment 
Cirrhosis/Kidney 
CI - Cirrhosis 
Comment - Kidney/Liver 
Methadone 
Dose 
CI 
Precaution 
Comment 
Opioid Treatment - Accordion 
Opioid Considerations  
Initiating Opioid Therapy 
Opioid Titration 
CI - Liver 
General - CI 
Disclaimer 
Anorexia 
Step 1: Consider the Underlying Causes of Anorexia 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Delirium 
Step 1: Consider the Underlying Causes of Delirium 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Depression 
Step 1: Consider the Underlying Causes of Depression 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Diarrhea 
Step 1: Consider the Underlying Causes of Diarrhea 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Edema 
Step 1: Consider the Underlying Causes of Edema 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Numbness/Tingling 
Step 1: Consider the Underlying Causes of Numbness & Tingling 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Shortness of Breath 
Step 1: Consider the Underlying Causes of Shortness of Breath 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Bupropion 
Dose 
CI 
Precaution 
Comment 
General 
General 
General  
General  
General  
General 
General  
General 
Sleep Disturbance 
Step 1: Consider the Underlying Causes of Sleep Disturbance 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Helpful Links 
End of Life Care 
Step 1: General Principles of End of Life Care 
Step 2: Non-pharmacological Management 
Step 3: Medical Management 
Step 4: Palliative Care Consult 
Pregabalin 
Dose 
CI 
Precaution 
Comment 
DEMO Symptom - Line of Treatment 
Step 1: Consider the Underlying Causes of DEMO Symptom - Line of Treatment 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Pregabalin (2) 
Dose 
CI 
Precaution 
Comment 
HIDE for kidney/liver 
Pregabalin (1) 
Dose 
CI 
Precaution 
Comment 
Kidney 
Liver 
Helpful Links 
References 
Med 2 
Dose 
CI 
Precaution 
Comment 
HF 
Hide HF 
How to use onecarepath 
Second Line Therapy (Stimulants) 
Bisacodyl 
Dose 
CI 
Precaution 
Comment 
Cancer - Dose 
General - CI 
General 
COPD Description 
Heart Failure Description 
Cirrhosis Description 
Advanced Chronic Kidney Disease Description 
Cancer Description 
Mild Symptoms: limited evidence exists for most medications 
test2 
Step 4: Palliative Care Specialist Consultation 
Terminal Care Considerations 
If pain persists add a non-opioid +/- adjuvant therapy 
If pain persists consider adding an opioid, +/- adjuvant, +/- non-opioid 
End of Life Care 
Melatonin 
Dose 
CI 
Precaution 
Comment 
Mirtazapine 
Dose 
CI 
Precaution 
Comment 
Trazodone 
Dose 
CI 
Comment 
Doxepin 
Dose 
Precaution 
Comment 
Moderate to severe symptoms 
Zopiclone 
Dose 
CI 
Precaution 
Comment 
Gabapentin 
Dose 
CI 
Precaution 
Comment 
Pregabalin 
Dose 
CI 
Precaution 
Comment 
Precaution - HF 
Dose Adjustment - CKD 
Dose Adjustment - Cirrhosis 
Comment - Kidney/Liver 
CI - Liver HE 
Dose adjust - Kidney 
Dose Adjust - Liver 
comment - kidney/liver 
Precaution 
General CI 
Fentanyl Transdermal Patch 
Liver - MasterHide 
Liver CI 
Acetaminophen 
Liver CI - MasterHide 
Pain - Neuropathic 
Pain - Nociceptive 
Restless Legs 
Constipation 
Dose 
CI 
Precaution 
Comment 
Dose 
CI 
Precaution 
Comment 
med 1 for step 7 
Dose 
CI 
Precaution 
Comment 
Fatigue 
Shortness of Breath 
Morphine  
Carbamazepine 
Liver Heart - MasterHide 
Kidney - MasterHide 
Liver CI 
Doxepin 
Dose 
CI 
Precaution 
Comment 
Liver Heart - MasterHide 
Acetaminophen 
Dose 
CI 
Precaution 
Comment 
Liver - MasterHide 
Fentanyl Transdermal Patch 
Dose 
CI 
Precaution 
Comment 
Liver-MasterHide 
Morphine 
Dose 
CI 
Precaution 
Comment 
Kidney - MasterHide 
Sodium-phosphate Enema (Fleet Enema) 
Dose 
CI 
Precaution 
Comment 
Kidney_Heart Failure - MasterHide 
Methylphenidate 
Dose 
CI 
Precaution 
Comment 
Modafinil 
Dose 
CI 
Precaution 
Comment 
Heart Failure - MasterHide 
Heart Failure - MasterHide 
Doxepin 
Dose 
CI 
Precaution 
Comment 
Heart Liver - MasterHide 
HF Liver - Hide 
Helpful Links 
References 
Helpful Links 
References 
Metoclopramide 
Dose 
CI 
Precaution 
Comment 
General 
Kidney precaution 
Kidney/Liver Dose 
General 
Domperidone 
Dose 
CI 
Precaution 
Comment 
Liver dose adjustment 
General 
Liver CI 
General 
Haloperidol 
Dose 
Precaution 
Kidney Dose 
Liver Dose 
General 
Kidney Precaution 
Contraindications 
Comment 
General 
Dimenhydrinate 
Dose 
CI 
Precaution 
Comment 
General 
General 
General 
Haloperidol 
Dose 
CI 
Precaution 
Comment 
General CI 
General 
Methotrimeprazine 
Liver-MasterHide 
Ondansetron 
Dose 
CI 
Precaution 
Comment 
Kidney Dose Adjustment 
Liver Dose Adjustment 
General  
Liver Precaution 
Olanzapine 
Dose 
CI 
Precaution 
Comment 
General 
Kidney CI 
General 
CINV treatment only 
Dose 
CI 
Precaution 
Comment 
Dexamethasone 
Dose 
CI 
Precaution 
Comment 
all conditions except cancer CI 
Dexamethasone 
Dose 
All conditions except cancer - MasterHide 
Precaution 
Comment 
Patient Pathway 
Provider Pathway 
Medication MasterHide 
Patient Pathway 
What is One:carepath 
Provider Resources 
Other 
FAQ 
About one:carepath 
Useful Links 
Useful Contacts 
Events & Newsletters 
Disclaimer & Privacy 
Quality Improvement 
Quality Improvement 
KPI's 
Glossary 
Choosing Supportive Care 
Provider Pathway 
Advance Care Planning 
Patient Symptom Guidelines 
Patient Handouts 
About the Provider Pathway 
Choosing Supportive Care 
Dose 1 
Confirm Comorbidities and Risk Stratify 
Engage Specialty Care 
Education Materials 
Patient Resources 
For Healthcare Providers 
For Patient 
Access to Tools & Best Practice Supports 
Symptom & Medical Management 
Prepare for Care Planning With Your Healthcare Providers 
Better Understand Your Health Conditions 
Healthcare Providers 
Patients/Family 
Prepare for Conversations About Your Wishes & Needs 
Manage Your Health Conditions 
Action Plans 
Provider Checklists 
Clinical Pathways 
Complimentary Treatments 
Helpful Links 
References 
Lidocaine 2.5% cream 
Gabapentin 
Dose 
CI 
Precaution 
Comment 
CI Cirrhosis 
Renal + Liver Precaution 
Pregabalin 
Dose 
Comment 
ESKD Dose Adjust 
ESKD Dose Adjust 
Hide (cirrhosis med only) 
CI 
Precaution 
Comment 
Cirrhosis CI 
CI 
Precaution 
General Precaution 
Comment 
general Comment 
Liver - CI 
General - CI 
General 
General 
Renal 
Not indicated except for liver 
Renal 
CI 
General 
Renal 
Renal 
General 
General 
Renal Dose 
COPD Dose 
General 
General 
Liver Dose 
Cirrhosis Dose 
CI 
Liver + Renal CI 
Precautions 
Liver + Renal 
Dose 
Renal + Liver CI 
Liver + Renal Precaution 
Liver CI 
Cirrhosis precaution 
hide for non liver or kidney 
hide for non liver or kidney 
hide for non-liver or kidney 
Helpful Links 
References 
Liver CI 
HF Precaution 
General 
Liver Dose 
General 
Liver CI 
CKD, Liver 
Ascites 
Step 1: Initial Workup 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Hepatic Encephalopathy 
Step 1: Consider the Underlying Causes of Hepatic Encephalopathy 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Hepatocellular Carcinoma 
Step 1: Consider the Underlying Causes of Hepatocellular Carcinoma 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
What is Worrying you right now? 
Your Health Conditions 
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Your Wishes and Preferences 
Symptom Management Guides  
Your Health Plan 
What is Shared Care Planning? 
Steps in Shared Care Planning 
What is Advance Care Planning? 
Your Green Sleeve 
Preparing for the Final Weeks & Days of Life 
Your Shared Care Plan 
Basic fluid workup (for patients who have had a thorough fluid analysis before): 
Extended ascites fluid workup (for patient having a first-tine paracentesis):  
Mild Ascites 
Spironolactone Monotherapy 
Dose 
CI 
Precaution 
Comment 
General Precaution 
Amiloride (Substitute for Spironolactone) 
Dose 
CI 
Precaution 
Comment 
Mild to Moderate Ascites 
Tense Ascites 
Lactulose (oral) 
Dose 
CI 
Precaution 
Comment 
If oral intake safe/tolerated 
If oral intake not safe/not tolerated 
Lactulose (nasogastric) 
If improvement start secondary prophylaxis 
Secondary Prophylaxis 
Dose 
CI 
Precaution 
Comment 
If no improvement 
Rifaximin 
Dose 
CI 
Precaution 
Comment 
Patient Symptom - Pain 
Step 1: Consider the Underlying Causes of Patient Symptom - Pain 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Patient Symptom - Pain 
Step 1: What can I try at home? 
Step 2: What treatment choices do I have? 
Step 3: Pharmacological Management 
Step 4: Pain Resources 
Tailored Outputs Based on Conditions 
Confirm Comorbidities 
End Of Life Guideline 
End of Life 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
CKD Associated Pruritus  
Step 1: Consider the Underlying Causes of CKD Associated Pruritus  
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Good Skin Care 
Complimentary Treatments 
Topical Treatment 
Systemic Treatment 
Pramoxine 
Dose 
CI 
Precaution 
Comment 
Capsaicin 0.025% or 0.075% Ointment 
Dose 
CI 
Precaution 
Comment 
Menthol, Camphor and Phenol are separate products that can be added to most creams, typically in the range of 0.3-1.0% 
Dose 
CI 
Precaution 
Comment 
 Gamma-Linolenic acid (GLA) 2.2% cream 
Dose 
CI 
Precaution 
Comment 
Lidocaine 2.5% cream 
Dose 
CI 
Precaution 
Comment 
Dose 
CI 
Precaution 
Comment 
Pregabalin 
Dose 
CI 
Precaution 
Comment 
Gabapentin 
Dose 
CI 
Precaution 
Comment 
ESKD Dose Adjustment 
Cirrhosis Dose 
Liver & Renal CI 
Liver & Renal  
ESKD Dose 
Liver Dose 
Risk Staging 
Self-Management & Lifestyle Modifications: General  
Establish Community Support & Referrals 
Advance Care Planning 
Palliative Care 
Final Weeks and Days of Life 
COPD 
Heart Failure 
Cirrhosis  
Advanced CKD 
Cancer  
COPD  
Heart Failure  
Cirrhosis  
Advanced CKD 
Cancer  
COPD 
Heart Failure 
Cirrhosis 
Advanced CKD 
Cancer 
COPD 
Heart Failure 
Cirrhosis 
Advanced CKD 
Cancer 
COPD 
Heart Failure 
Cirrhosis 
Advanced CKD 
Cancer 
Message 
COPD 
Heart Failure 
Cirrhosis 
Advanced CKD 
Cancer 
Dosing for Combination Diuretics 
Dose 
CI 
Precaution 
Comment 
Large-volume (≥ 5L) paracentesis AND start combination diuretics if no contraindications 
Dose 
CI 
Precaution 
Comment 
Diagnostic Criteria for Refractory Ascites & Management 
Monitoring for Patients on Diuretics 
How to titrate up diuretics 
References 
Additional Resources 
COPD  
Step 1: COPD Management 
Step 2: Pharmacological Management 
Heart Failure Management 
Step 1: Consider the Underlying Causes of Heart Failure Management 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 3: Exacerbation Management 
Dose 
CI 
Precaution 
Comment 
Dose 
CI 
Precaution 
Comment 
Examples of converting oral to subcutaneous administration 
When to Consult a Palliative Care Specialist 
EMS Palliative and End of Life Care Assess, Treat, and Refer (EMS PEOLC ATR) Initiative 
Services required for caring for patients at home, location of care and location of death 
Step 5: What Happens After Death? 
Symptom Management Near the End of Life 
Pain  
Breathlessness 
Fluid Management 
Respiratory Secretions 
Constipation 
Fatigue & Sleep Disturbance 
Restless Legs Syndrome 
Delirium & Agitation  
Poor Appetite & Intake  
Muscle Cramps 
Helpful Links 
Shared Care Plan 
COPD 
Heart Failure 
Cirrhosis 
Advanced CKD 
Cancer 
Muscle Cramps 
Step 1: Consider the Underlying Causes of Muscle Cramps 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Symptom Management 
Medical Management 
General 
Smoking 
 Immunization 
 Nutrition 
 Exercise 
Social Determinants of Health 
 Home Care 
Advance Care Planning 
Salt Intake 
Fluid Intake  
Alcohol  
 Obesity Counselling 
Mood and Stress Management  
Resources 
Pulmonary Rehabilitation 
Calgary COPD and Asthma Program  (CCAP) 
Alberta Healthy Living Program  
Community Paramedics (CP) 
Home Care (COPD homecare specific teams) 
Alberta Quits  
Other Resources 
Your Support Team 
 Palliative & End of Life Care 
Symptom Management for Advanced CKD 
Constipation 
What causes constipation? 
What you can do to help manage your constipation 
When you should talk to your healthcare provider 
Medication 1 
Dose 
CI 
Precaution 
Comment 
Mona 
Step 1: Consider the Underlying Causes of Mona 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Medication 1 
Dose 
CI 
Precaution 
Comment 
CKD 
Acidosis Guideline 
Acidosis (Metabolic) - Clinical Algorithm  
Dosing Chart for Sodium Bicarbonate 
Additional Resources: 
Blood Pressure Guideline 
Additional Resources 
Sodium/Fluid Statement 
Sodium Intake 
Fluid Intake 
Rehydration if patients are not able to drink orally 
Considerations at End of Life 
Nausea & Vomiting 
Accordion Container 
What you can do to help manage nausea & vomiting? 
When you should talk to my healthcare team? 
Links 
Accordion Container 
Links 
Pain 
Accordion Container 
What you can do to help manage your pain 
When you should talk to your healthcare team 
Links 
Shortness of Breath 
Accordion Container 
What causes shortness of breath  
What you can do to help manage shortness of breath  
When you should talk to your healthcare team 
Links 
Anemia Guideline 
Iron Protocol for Conservatively Managed Patients 
HGB/ESA Protocol & Dose Adjustment Schedule for darbepoietin (Aranesp®) 
Additional Resources 
Calcium/Phosphorus Guideline 
Dose Adjustment Guideline for Phosphate Binders – Recommended Initial Calcium Dosing 
Dose Adjustment Guideline for Non-Calcium Based Phosphate Binders (may be used alone or as an adjuvant therapy) 
High Calcium Clinical Guideline 
Lipids Guideline 
Additional Resources 
Potassium Guideline 
Potassium - Clinical Algorithm  
Additional Resources 
Vitamin D Statement 
Considerations at End of Life: 
Additional Resources 
Calcitriol (active form of vitamin D, e.g. Rocaltrol) 
Glossary 
acc1 
acc item1 
fasdf 
p1 
replace  
Container 
Med1 
Dose 
CI 
Precaution 
Comment 
repalce when HF 
hide when cancer 
acc no 1 
Med 1 
Dose 
CI 
Precaution 
Comment 
replace when HF 
Hide when Cancer 
Shared Care Planning 
Supportive Care 
Health Condition 
Chronic Disease 
Preferences 
Health Plan 
Healthcare Team 
Advance Care Planning or ACP 
Personal Directive  
Enduring Power Attorney  
Goals of Care   (Designation) or GoC 
“Greensleeve”  
Palliative care 
End of Life Care 
Accordion Container 
Additional Resources 
What is Palliative Care? 
Accordion Container 
Darbepoetin starting dose when Hgb < 95 g/L and iron replete. 
Darbepoetin adjustment schedule if Hgb BELOW target: 
Darbepoetin adjustment schedule if Hgb ABOVE target or rising significantly: 
Dose Adjustment Schedule for epoetin alpha (Eprex ®) 
Glossary 
Symptom and Medical Management 
Patient Handouts 
Maintenance: Calcium Dosing Guideline 
Additional Resources 
What is End of Life Care? 
Helpful Links 
References 
Helpful Links 
References 
References 
Helpful Links 
References 
Additional Resources 
References 
Additional Resources 
References 
Additional Resources 
References 
Hide for non liver or kidney 
Not indicated except in liver 
Step 1: Continue Goals of Care Discussions 
References 
Hide for HF 
except HF 
General 
General 
General 
General 
General 
Restless Legs 
Lack of Appetite 
Depression & Anxiety 
Fatigue 
Muscle Cramps 
Numbness & Tingling 
Taste Changes 
Diarrhea 
Dehydration 
Itchiness 
Swelling 
Difficulty Swallowing 
Sleep Problems 
Palliative Care 
Accordion Container 
What causes restless leg syndrome 
What you can do to help manage your restless leg syndrome 
When you should talk to your healthcare team 
Accordion Container 
What causes a lack of appetite 
What you can do to help manage your lack of appetite 
When you should talk to your healthcare team 
Accordion container 
What causes depression & anxiety 
What you can do to help manage your depression & anxiety 
When you should talk to your healthcare team 
Accordion container 
What causes fatigue 
What you can do to help manage you fatigue 
When you should talk to your healthcare team 
Accordion container 
What causes muscle cramps 
What you can do to help manage your muscle cramps 
Accordion container 
When you should talk to your healthcare team 
What causes numbness & tingling 
What you can do to help manage your numbness & tingling 
When to talk to your healthcare team 
Accordion Container 
What causes taste changes? 
What you can do to help manage your taste changes 
When to talk to your healthcare team 
Accordion Container 
What causes diarrhea? 
What you can do to help manage your diarrhea 
When to talk to your healthcare team 
Accordion Container 
What causes dehydration? 
What you can do to help manage your dehydration 
When to talk to your healthcare team 
Accordion Container 
What causes itchiness? 
What you can do to help manage your itchiness 
When to talk to your healthcare team 
Accordion Container 
What causes swelling? 
What you can do to help manage your swelling 
When to talk to your healthcare team 
Accordion Container 
What causes sleep problems? 
What you can do to help manage your sleep problems 
When to talk to your healthcare team 
What causes nausea & vomiting? 
Accordion Container 
What you can do to help manage your difficulty with swallowing 
When to talk to your healthcare team 
What causes difficulty in swallowing? 
What causes nausea & Vomiting 
What causes pain 
Accordion Container 
what can I expect in the last weeks and days of life? 
What will happen if my family & friends can't care for me at home? 
Helpful links to learn more about palliative and end of life care in Alberta 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Links 
Cancer Management 
Step 1: Consider the Underlying Causes of Cancer Management 
Step 2: Non-pharmacological Management 
Step 3: Pharmacological Management 
Step 4: Palliative Care Consult 
Advance Care Planning 
Palliative & End of Life 
Access to Resources 
Topical Compounded Products 
Dose 
CI 
Precaution 
Comment 
Caution 
General-Caution 
Topical Compounded Products 
Dose 
CI 
Precaution 
Comment 
General Condition 
condition for HF & KD 
General CI 
Additional Resources 
Lemborexant 
Dose 
CI 
Precaution 
Comment 
Hide for Kidney and Cirrhosis 
Hide for Cancer COPD HF 
Sertraline 
Dose 
CI 
Precaution 
Comment 
CI-Genernal 
General 
CI for Cirrhosis 
Living with Heart Failure 
Living with COPD 
Additional Resources 
                    
                        Actoin 
                        Replace 
Append Warning 
Append Alarm 
Append Note 
Hide