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Section 2
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Integrated Supportive Care
What is one:carepath?
Who is One:carepath for?
Patient Symptoms
About You & Your Health Conditions
Managing Your Health Condition
Your Shared Care Plan
Your Advance Care Planning
Patient Portal Home Page
Provider Pathway Content
Diease Area Description
Confirm Comorbidities
Hero
Quick Access
Posters
Call to Action
Highlighted Features
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Navbar
Integrated Supportive Care
Home
Interactive Clinical Assessment
Patients
Content
Symptom
Fatigue
STEP 1: IDENTIFY AND TREAT POTENTIAL REVERSIBLE CAUSES
Disease Area (KF)
Anxiety/Depression
Breathlessness
Constipation
Edema
Kidney
COPD
Heart
Liver
Cancer
Fatigue
New General Symptom Management Content - Symptom 1
New Section
Cause 1
Edema
Step 1. General Symptom Management
New Section
Cause 1
Step 4. Palliative Care Consult
Fatigue
New General Symptom Management Content - Symptom 1
New Section
Cause 1
Anxiety/Depression
Step 1: General Symptom Management
New Section
Cause 1
STEP 2: GENERAL Non-Pharmacological
Non-Pharmacological Symptom Nuances
Non-Pharmacological: Disease Specific Symptom Management
Cause 1
STEP 3: Pharmacological
Liver Nuance
Kidney Nuance
Step 4: Palliative Care Consult
Constipation old
STEP 2: Non-Pharmacological Management
STEP 3: Pharmacological Management
STEP 4: Palliative Care Consult
STEP 2: NON-PHARMACOLOGICAL MANAGEMENT
STEP 3: PHARMACOLOGICAL MANAGEMENT
HEART FAILURE
CIRRHOSIS
KIDNEY FAILURE
ABOUT PAIN: GENERAL DESCRIPTION & DEFINITION
STEP 1: IDENTIFY AND TREAT POTENTIAL REVERSIBLE CAUSES
STEP 2: NON-PHARMACOLOGICAL MANAGEMENT
STEP 3: PHARMACOLOGICAL MANAGEMENT
KIDNEY DISEASE - NEUROPATHIC
KIDNEY DISEASE - NOCICEPTIVE
STEP 4: PALLIATIVE CARE CONSULT
PHARMACOLOGICAL PALLIATIVE CARE END OF LIFE NEUROPATHIC PAIN
PHARMACOLOGICAL PALLIATIVE CARE END OF LIFE NOCICEPTIVE PAIN
Superficial pain
Bone
Soft Tissue
Muscle Relaxants
Visceral
Dexamethasone
Bisphosphonate – Clodronate 1600-2400 mg PO daily
Denosumab 120 mg SC every 4 weeks
STEP 4: PALLIATIVE CARE CONSULT Version 2
NSAID (systemic)
NSAID (topical)
Diazepam
Baclofen
Tizanidine
GFR 0-7
GFR 8-15
GFR 15-30
GFR 30+
EFS Severe
EFS Not Severe
Other Assessment Tool
EFS Severe
EFS Not Severe
EFS Severe
EFS Not Severe
Heart Failure
FEV1
FEV2
EFS Severe
EFS Not Severe
Weight
Another Tool
New Measurement Level
Test Disease Area
Fatigue old
STEP 1: Consider the Underlying Causes of Fatigue
STEP 2: Non Pharmacological Management of Fatigue
STEP 3: Pharmacological Management v1 - Modelled after Med Table
STEP 4: Palliative Care Consult
Nausea & Vomiting
Step 1: Consider the Underlying Causes of Nausea & Vomiting
Step 2: Non-Pharmacological Management
STEP 4: Palliative Care Consult
Step 3: Pharmacological Management
Dexamethasone-Append-Cancer
HF-Replace-Buproprion
Step 3: Pharmacological Management v2 - Fewest Nodes - Better management
Dexamethasone-Append-Cancer
STEP 3: Pharmacological Management V3 - Will not work as this does not align with wholistic approach
Heart Failure
Cancer
STEP 3: Pharmacological Management v4 - Most Nodes and Difficult to Manage
Modafinil (Provigil)
Methylphenidate (Ritalin)
Bupropion
Modafinil-<>HF
Methyphenidate <> HF
Modafinil-Cirrhosis-ReduceDose <> HF
KIdney
STEP 3: Pharmacological Management v5 - Using Hide
Dexamethasone
Reduce Dose-Cirrhosis - Need to create nuance to a nuance
Modafinil
Dexamethasone
Methylphenidate (Ritalin)
Reduce Dose Cirrhosis
STEP 3: Pharmacological Management of Fatigue
Bupropion
Methyphenidate & Modafinil
Continue with algorithm
Dexamethasone
Bisacodyl; Peristaltic stimulant
Cancer Adjusted Dose
Methyphenidate & Modafinil
Rule-Hide when HF selected
Bupropion
Rule-Hide when Cirrhosis selected
Psyllium (Metamucil)
Polyethylene glycol (PEG 3350) (LAX-A-DAY); Osmotic laxative
Lactulose or Sorbitol; Osmotic laxative
Sennosides (SenekotÒ); Peristaltic stimulant
Glycerin Suppository
Sodium-phosphate enema (Fleet Enema)
Magnesium citrate or hydroxide or sulfate (Epsom salt)
Methylnaltexone (RelistorÒ); Peripherally acting μ-opioid receptor antagonists (PAMORAs)
Kidney Disease Dose Adjustment
Naloxegol (MovantikÒ); Peripherally acting μ-opioid receptor antagonists (PAMORAs)
KidneyDiseaseDoseAdjustment
CirrhosisChildPughCAvoidUse
Prucalopride; Prokinetics
KidneyDiseaseDoseAdjustment
Manual Disimpaction; for severe constipation
Cholestatic Pruritus
Step 1: Consider the Underlying Causes of Pruritus
Step 2: Non-pharmacological Management
Good Skin Care and Moisturizers
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Is this terminal phase of life? yes
Is this terminal phase of life? no
Topical Treatment
Pramoxine
Capsaicin 0.025% or 0.075% Ointment
Menthol, Camphor and Phenol are separate products that can be added to most creams, typically in the range of 0.3-1.0%
Gamma-Linolenic acid (GLA) 2.2% cream
Systemic Treatment
Doxepin
CI
Precaution
Comment
Cholestyramine
Rifampin
CI
Precaution
Liver Cirrhosis
Naltrexone
CI
Precaution
Comment
Restless Legs
Step 1: Consider the Underlying Causes of Restless Leg Syndrome
Step 2: Consider Non-Pharmacological Management
Step 3: Pharmacological Management
Gabapentin
Dose
CKD Dose
Liver Dose
Pregabalin
Pramipexole (Mirapex)
Rotigotine (Neupro)
CI
Precaution
Comment
CKD, Liver
Dose
CKD
CI
Precaution
Comment
Dose
CI
Precaution
Comment
Dose
CI
Precaution
Comment
Ropinirole (Requip)
Dose
CI
Precaution
Comment
Midazolam (Versed)
Dose
CKD,Cir,CAN,HF
COPD
CI
Precaution
Comment
CKD,HF
COPD
Neuropathic Pain (OLD)
Step 1: Consider the Underlying Causes of Neuropathic Pain
Step 2: Non-Pharmacological Management of Neuropathic Pain
Step 3: Pharmacological Management of Neuropathic Pain
Step 4: Palliative Care Consult
Non-Opioid Treatment
Step 2: Non-Opioid
Opioid Treatment
Acetaminophen
Dose
CI
Precaution
Comment
Diclofenac Gel
Dose
Comment
Hydromorphone
Dose
CI
Precaution
Comment
Fentanyl Transdermal Patch
Dose
CI
Precaution
Comment
Methadone
Dose
CI
Precaution
Comment
Nociceptive Pain (backup -Old)
Step 1: Consider the Underlying Causes of Nociceptive Pain
Step 2: Non-pharmacological Management of Nociceptive Pain
Step 3: Pharmacological Management of Nociceptive Pain
Step 4: Palliative Care Consult
Non-opioids (for mild pain (typically >3/10)
Step 2: Moderate Pain (4-6/10)
Opioids
Step 5: Patient Education & Self-Care
Gabapentin
Dose
CI
Comment
Pregabalin
Dose
CI
Precaution
Comment
Amitriptyline
Dose
CI
Precaution
Comment
Acetaminophen
Dose
CI
Precaution
Comment
Hydromorphone
Dose
CI
Precaution
Comment
Fentanyl Transdermal Patch
Dose
CI
Precaution
Comment
Methadone
Dose
CI
Precaution
Comment
Step 5 Patient Education & Self Care
Step 5: Patient Education and Self Care
When is an opioid indicated?
Precaution
General
General
Fatigue
Step 1: Consider the Underlying Causes of Fatigue
Step 2: Non-pharmacological Management of Fatigue
Step 3: Pharmacological Management of Fatigue
Step 4: Palliative Care Consult
General - Precaution
Methyphenidate
Dose
CI
Precaution
HF
Modafinil
Dose
CI
Precaution
HF
Dexamethasone
Dose
CI
Precaution
Constipation
Step 1: Consider the Underlying Causes of Constipation
Step 2: Non-pharmacological Management of Constipation
Step 3: Pharmacological Management of Constipation
Step 4: Palliative Care Consult
Psyllium Husk
Dose
CI
Comment
General
Precaution
Polyethylene Glycol (PEG 3350)
Dose
CI
Precaution
Comment
Sennosides
Dose
CI
Precaution
Comment
Bisacodyl
Dose
CI
Precaution
Comment
Cancer
Glycerin or Bisacodyl Suppository
Dose
CI
Precaution
Comment
KF
Sodium-phosphate Enema (Fleet Enema)
Dose
CI
Precaution
Magnesium citrate or hydroxide or sulfate (Epsom Salt)
Dose
Precaution
Methylnaltexone
Dose
CI
Precaution
Comment
KF
Cirrhosis
General
Cirrhosis
Secretagogues (Linaclotide)
Prokinetics (Prucalopride)
Liver Renal - Precaution
General - CI
General - CI
General - P
General - CI
General - P
General - CI
General - P
COPD - P
Liver - CI
General
General
Lactulose
Dose
CI
Precaution
Comment
General
General
General
General
General
General
General
General
General
Dose - CKD
General - CI
General - Precaution
General - Precaution
High Mineral Oil Enema
Dose
CI
Precaution
Comment
General - PI
General - CI
Dose - CKD
General - CI
Ducolax Suppository
Dose
CI
Precaution
Comment
General - CI
General - Precaution
Demo Medication
Dose
CI
Precaution
Comment
Alarm When COPD
Warning when Heart Failure
Hide When Cirrhosis
Replace When Kidney Disease
Hide When Cancer
Append When Cancer
Demo Symptom
Step 1: Consider the Underlying Causes of Demo Symptom
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
New Med 1
Dose
CI
Precaution
Comment
General - CI
General - Precaution
CKD - Dose
CKD - Dose
General - CI
General - precaution
Comment - HF
Amitriptyline
Dose
CI
Precaution
Comment
General - CI
General - precaution
Liver - CI
Acetominophen
Dose
CI
Precaution
Comment
General - Precaution
Cirrhosis - CI (HIDE)
Liver - CI
HIDE
NOT HF
General
General
General
General
General
General
HIDE Liver
CI
General
Non-Opioid Treatment - Accordion
General Information
Reference Accordion
References
Opioid Treatment - Accordion
Opioid Considerations
Initiating Opioid Therapy
Opioid Titration
Helpful Links
Pain - Neuropathic
Step 1: Consider the Underlying Causes of Neuropathic Pain
Step 2: Non-Pharmacological Management of Neuropathic Pain
Step 3: Pharmacological Management of Neuropathic Pain
Step 4: Palliative Care Consult
Reference Accordion
Helpful Links
References
2. Non-Opioid Therapy
3. Opioid Therapy
Hydromorphone
Dose
CI
Precaution
Comment
Fentanyl Transdermal Patch
Dose
CI
Precaution
Comment
Methadone
Dose
CI
Precaution
Comment
Opioid Treatment - Accordion
Opioid Considerations
Initiating Opioid Therapy
Opioid Titration
Gabapentin
Dose
CI
Precaution
Comment
Pregabalin
Dose
CI
Precaution
Comment
Amitriptyline
Dose
CI
Precaution
Comment
Acetaminophen
Dose
CI
Precaution
Comment
Non-Opioid Treatment - Accordion
General Information
CKD - Dose
General - Precaution
CKD - Dose
General - precaution
Comment - kidney/liver
General - CI
General - precaution
General - Precaution
General
General
General
Comment - HF
CKD/Cirrhosis
Special Considerations for Opioid Induced Constipation (OIC)
Dose - Cirrhosis
Peripherally acting μ-opioid receptor antagonists (PAMORAS)
HF/CKD Hide
Methadone (2)
Diclofenac Gel
Dose
CI
Precaution
Comment
Kidney/Cirrhosis
Precaution - Kidney Failure
Morphine (immediate release)
Dose
CI
Precaution
Comment
General
CI - Cirrhosis
Buprenorphine
Dose
CI
Precaution
Comment
Oxycodone
Dose
CI
Precaution
Comment
Cirrhosis/Kidney
CI - Cirrhosis
Comment - Kidney/Liver
Kidney CI
Dose - Cirrhosis
Comment - kidney/liver
Precaution - HF
Cirrhosis - dose
General - comment
CI - liver/hepatic encephalopathy
Carbamazepine
Dose
CI
Precaution
Comment
General - CI
CI - Cirrhosis/HF
General - Precaution
Dose adjust - CKD/Cirrhosis
General Comment
Doxepin
Dose
CI
Precaution
Comment
General - CI
CI - HF/Cirrhosis
General - CI
1. Start with Adjuvant Therapy
Pain - Nociceptive
Step 1: Consider the Underlying Causes of Nociceptive Pain
Step 2: Non-pharmacological Management of Nociceptive Pain
Step 3: Pharmacological Management of Nociceptive Pain
Step 4: Palliative Care Consult
First Line Therapy (Bulk Forming Laxatives)
First Line Therapy (Osmotic Laxatives)
First Line Therapy (Stimulant Laxatives)
Second Line Therapy (Suppositories)
Third Line Therapy (Alternative Treatments)
Fourth Line Therapy (Special Considerations) - Specialist referral recommended
Comment
Contraindication
Comment
General
Non-Opioid Therapy
Acetaminophen
Dose
CI
Precaution
Comment
Cirrhosis - CI (HIDE)
Diclofenac Gel
Dose
CI
Precaution
Comment
Non-Opioid Treatment - Accordion
Opioid Therapy
Hydromorphone
Dose
CI
Precaution
Comment
Kidney/Cirrhosis
Fentanyl Transdermal Patch
Dose
CI
Precaution
Comment
Precaution - Kidney Failure
Morphine (immediate release)
Dose
CI
Precaution
Comment
CI - Cirrhosis
Hide - Kidney
Buprenorphine
Dose
CI
Precaution
Comment
Oxycodone
Dose
CI
Precaution
Comment
Cirrhosis/Kidney
CI - Cirrhosis
Comment - Kidney/Liver
Methadone
Dose
CI
Precaution
Comment
Opioid Treatment - Accordion
Opioid Considerations
Initiating Opioid Therapy
Opioid Titration
CI - Liver
General - CI
Disclaimer
Anorexia
Step 1: Consider the Underlying Causes of Anorexia
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Delirium
Step 1: Consider the Underlying Causes of Delirium
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Depression
Step 1: Consider the Underlying Causes of Depression
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Diarrhea
Step 1: Consider the Underlying Causes of Diarrhea
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Edema
Step 1: Consider the Underlying Causes of Edema
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Numbness/Tingling
Step 1: Consider the Underlying Causes of Numbness & Tingling
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Shortness of Breath
Step 1: Consider the Underlying Causes of Shortness of Breath
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Bupropion
Dose
CI
Precaution
Comment
General
General
General
General
General
General
General
General
Sleep Disturbance
Step 1: Consider the Underlying Causes of Sleep Disturbance
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Helpful Links
End of Life Care
Step 1: General Principles of End of Life Care
Step 2: Non-pharmacological Management
Step 3: Medical Management
Step 4: Palliative Care Consult
Pregabalin
Dose
CI
Precaution
Comment
DEMO Symptom - Line of Treatment
Step 1: Consider the Underlying Causes of DEMO Symptom - Line of Treatment
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Pregabalin (2)
Dose
CI
Precaution
Comment
HIDE for kidney/liver
Pregabalin (1)
Dose
CI
Precaution
Comment
Kidney
Liver
Helpful Links
References
Med 2
Dose
CI
Precaution
Comment
HF
Hide HF
How to use onecarepath
Second Line Therapy (Stimulants)
Bisacodyl
Dose
CI
Precaution
Comment
Cancer - Dose
General - CI
General
COPD Description
Heart Failure Description
Cirrhosis Description
Advanced Chronic Kidney Disease Description
Cancer Description
Mild Symptoms: limited evidence exists for most medications
test2
Step 4: Palliative Care Specialist Consultation
Terminal Care Considerations
If pain persists add a non-opioid +/- adjuvant therapy
If pain persists consider adding an opioid, +/- adjuvant, +/- non-opioid
End of Life Care
Melatonin
Dose
CI
Precaution
Comment
Mirtazapine
Dose
CI
Precaution
Comment
Trazodone
Dose
CI
Comment
Doxepin
Dose
Precaution
Comment
Moderate to severe symptoms
Zopiclone
Dose
CI
Precaution
Comment
Gabapentin
Dose
CI
Precaution
Comment
Pregabalin
Dose
CI
Precaution
Comment
Precaution - HF
Dose Adjustment - CKD
Dose Adjustment - Cirrhosis
Comment - Kidney/Liver
CI - Liver HE
Dose adjust - Kidney
Dose Adjust - Liver
comment - kidney/liver
Precaution
General CI
Fentanyl Transdermal Patch
Liver - MasterHide
Liver CI
Acetaminophen
Liver CI - MasterHide
Pain - Neuropathic
Pain - Nociceptive
Restless Legs
Constipation
Dose
CI
Precaution
Comment
Dose
CI
Precaution
Comment
med 1 for step 7
Dose
CI
Precaution
Comment
Fatigue
Shortness of Breath
Morphine
Carbamazepine
Liver Heart - MasterHide
Kidney - MasterHide
Liver CI
Doxepin
Dose
CI
Precaution
Comment
Liver Heart - MasterHide
Acetaminophen
Dose
CI
Precaution
Comment
Liver - MasterHide
Fentanyl Transdermal Patch
Dose
CI
Precaution
Comment
Liver-MasterHide
Morphine
Dose
CI
Precaution
Comment
Kidney - MasterHide
Sodium-phosphate Enema (Fleet Enema)
Dose
CI
Precaution
Comment
Kidney_Heart Failure - MasterHide
Methylphenidate
Dose
CI
Precaution
Comment
Modafinil
Dose
CI
Precaution
Comment
Heart Failure - MasterHide
Heart Failure - MasterHide
Doxepin
Dose
CI
Precaution
Comment
Heart Liver - MasterHide
HF Liver - Hide
Helpful Links
References
Helpful Links
References
Metoclopramide
Dose
CI
Precaution
Comment
General
Kidney precaution
Kidney/Liver Dose
General
Domperidone
Dose
CI
Precaution
Comment
Liver dose adjustment
General
Liver CI
General
Haloperidol
Dose
Precaution
Kidney Dose
Liver Dose
General
Kidney Precaution
Contraindications
Comment
General
Dimenhydrinate
Dose
CI
Precaution
Comment
General
General
General
Haloperidol
Dose
CI
Precaution
Comment
General CI
General
Methotrimeprazine
Liver-MasterHide
Ondansetron
Dose
CI
Precaution
Comment
Kidney Dose Adjustment
Liver Dose Adjustment
General
Liver Precaution
Olanzapine
Dose
CI
Precaution
Comment
General
Kidney CI
General
CINV treatment only
Dose
CI
Precaution
Comment
Dexamethasone
Dose
CI
Precaution
Comment
all conditions except cancer CI
Dexamethasone
Dose
All conditions except cancer - MasterHide
Precaution
Comment
Patient Pathway
Provider Pathway
Medication MasterHide
Patient Pathway
What is One:carepath
Provider Resources
Other
FAQ
About one:carepath
Useful Links
Useful Contacts
Events & Newsletters
Disclaimer & Privacy
Quality Improvement
Quality Improvement
KPI's
Glossary
Choosing Supportive Care
Provider Pathway
Advance Care Planning
Patient Symptom Guidelines
Patient Handouts
About the Provider Pathway
Choosing Supportive Care
Dose 1
Confirm Comorbidities and Risk Stratify
Engage Specialty Care
Education Materials
Patient Resources
For Healthcare Providers
For Patient
Access to Tools & Best Practice Supports
Symptom & Medical Management
Prepare for Care Planning With Your Healthcare Providers
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Healthcare Providers
Patients/Family
Prepare for Conversations About Your Wishes & Needs
Manage Your Health Conditions
Action Plans
Provider Checklists
Clinical Pathways
Complimentary Treatments
Helpful Links
References
Lidocaine 2.5% cream
Gabapentin
Dose
CI
Precaution
Comment
CI Cirrhosis
Renal + Liver Precaution
Pregabalin
Dose
Comment
ESKD Dose Adjust
ESKD Dose Adjust
Hide (cirrhosis med only)
CI
Precaution
Comment
Cirrhosis CI
CI
Precaution
General Precaution
Comment
general Comment
Liver - CI
General - CI
General
General
Renal
Not indicated except for liver
Renal
CI
General
Renal
Renal
General
General
Renal Dose
COPD Dose
General
General
Liver Dose
Cirrhosis Dose
CI
Liver + Renal CI
Precautions
Liver + Renal
Dose
Renal + Liver CI
Liver + Renal Precaution
Liver CI
Cirrhosis precaution
hide for non liver or kidney
hide for non liver or kidney
hide for non-liver or kidney
Helpful Links
References
Liver CI
HF Precaution
General
Liver Dose
General
Liver CI
CKD, Liver
Ascites
Step 1: Initial Workup
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Hepatic Encephalopathy
Step 1: Consider the Underlying Causes of Hepatic Encephalopathy
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Hepatocellular Carcinoma
Step 1: Consider the Underlying Causes of Hepatocellular Carcinoma
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
What is Worrying you right now?
Your Health Conditions
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Your Wishes and Preferences
Symptom Management Guides
Your Health Plan
What is Shared Care Planning?
Steps in Shared Care Planning
What is Advance Care Planning?
Your Green Sleeve
Preparing for the Final Weeks & Days of Life
Your Shared Care Plan
Basic fluid workup (for patients who have had a thorough fluid analysis before):
Extended ascites fluid workup (for patient having a first-tine paracentesis):
Mild Ascites
Spironolactone Monotherapy
Dose
CI
Precaution
Comment
General Precaution
Amiloride (Substitute for Spironolactone)
Dose
CI
Precaution
Comment
Mild to Moderate Ascites
Tense Ascites
Lactulose (oral)
Dose
CI
Precaution
Comment
If oral intake safe/tolerated
If oral intake not safe/not tolerated
Lactulose (nasogastric)
If improvement start secondary prophylaxis
Secondary Prophylaxis
Dose
CI
Precaution
Comment
If no improvement
Rifaximin
Dose
CI
Precaution
Comment
Patient Symptom - Pain
Step 1: Consider the Underlying Causes of Patient Symptom - Pain
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Patient Symptom - Pain
Step 1: What can I try at home?
Step 2: What treatment choices do I have?
Step 3: Pharmacological Management
Step 4: Pain Resources
Tailored Outputs Based on Conditions
Confirm Comorbidities
End Of Life Guideline
End of Life
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
CKD Associated Pruritus
Step 1: Consider the Underlying Causes of CKD Associated Pruritus
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Good Skin Care
Complimentary Treatments
Topical Treatment
Systemic Treatment
Pramoxine
Dose
CI
Precaution
Comment
Capsaicin 0.025% or 0.075% Ointment
Dose
CI
Precaution
Comment
Menthol, Camphor and Phenol are separate products that can be added to most creams, typically in the range of 0.3-1.0%
Dose
CI
Precaution
Comment
Gamma-Linolenic acid (GLA) 2.2% cream
Dose
CI
Precaution
Comment
Lidocaine 2.5% cream
Dose
CI
Precaution
Comment
Dose
CI
Precaution
Comment
Pregabalin
Dose
CI
Precaution
Comment
Gabapentin
Dose
CI
Precaution
Comment
ESKD Dose Adjustment
Cirrhosis Dose
Liver & Renal CI
Liver & Renal
ESKD Dose
Liver Dose
Risk Staging
Self-Management & Lifestyle Modifications: General
Establish Community Support & Referrals
Advance Care Planning
Palliative Care
Final Weeks and Days of Life
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
Message
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
Dosing for Combination Diuretics
Dose
CI
Precaution
Comment
Large-volume (≥ 5L) paracentesis AND start combination diuretics if no contraindications
Dose
CI
Precaution
Comment
Diagnostic Criteria for Refractory Ascites & Management
Monitoring for Patients on Diuretics
How to titrate up diuretics
References
Additional Resources
COPD
Step 1: COPD Management
Step 2: Pharmacological Management
Heart Failure Management
Step 1: Consider the Underlying Causes of Heart Failure Management
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 3: Exacerbation Management
Dose
CI
Precaution
Comment
Dose
CI
Precaution
Comment
Examples of converting oral to subcutaneous administration
When to Consult a Palliative Care Specialist
EMS Palliative and End of Life Care Assess, Treat, and Refer (EMS PEOLC ATR) Initiative
Services required for caring for patients at home, location of care and location of death
Step 5: What Happens After Death?
Symptom Management Near the End of Life
Pain
Breathlessness
Fluid Management
Respiratory Secretions
Constipation
Fatigue & Sleep Disturbance
Restless Legs Syndrome
Delirium & Agitation
Poor Appetite & Intake
Muscle Cramps
Helpful Links
Shared Care Plan
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
Muscle Cramps
Step 1: Consider the Underlying Causes of Muscle Cramps
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Symptom Management
Medical Management
General
Smoking
Immunization
Nutrition
Exercise
Social Determinants of Health
Home Care
Advance Care Planning
Salt Intake
Fluid Intake
Alcohol
Obesity Counselling
Mood and Stress Management
Resources
Pulmonary Rehabilitation
Calgary COPD and Asthma Program (CCAP)
Alberta Healthy Living Program
Community Paramedics (CP)
Home Care (COPD homecare specific teams)
Alberta Quits
Other Resources
Your Support Team
Palliative & End of Life Care
Symptom Management for Advanced CKD
Constipation
What causes constipation?
What you can do to help manage your constipation
When you should talk to your healthcare provider
Medication 1
Dose
CI
Precaution
Comment
Mona
Step 1: Consider the Underlying Causes of Mona
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Medication 1
Dose
CI
Precaution
Comment
CKD
Acidosis Guideline
Acidosis (Metabolic) - Clinical Algorithm
Dosing Chart for Sodium Bicarbonate
Additional Resources:
Blood Pressure Guideline
Additional Resources
Sodium/Fluid Statement
Sodium Intake
Fluid Intake
Rehydration if patients are not able to drink orally
Considerations at End of Life
Nausea & Vomiting
Accordion Container
What you can do to help manage nausea & vomiting?
When you should talk to my healthcare team?
Links
Accordion Container
Links
Pain
Accordion Container
What you can do to help manage your pain
When you should talk to your healthcare team
Links
Shortness of Breath
Accordion Container
What causes shortness of breath
What you can do to help manage shortness of breath
When you should talk to your healthcare team
Links
Anemia Guideline
Iron Protocol for Conservatively Managed Patients
HGB/ESA Protocol & Dose Adjustment Schedule for darbepoietin (Aranesp®)
Additional Resources
Calcium/Phosphorus Guideline
Dose Adjustment Guideline for Phosphate Binders – Recommended Initial Calcium Dosing
Dose Adjustment Guideline for Non-Calcium Based Phosphate Binders (may be used alone or as an adjuvant therapy)
High Calcium Clinical Guideline
Lipids Guideline
Additional Resources
Potassium Guideline
Potassium - Clinical Algorithm
Additional Resources
Vitamin D Statement
Considerations at End of Life:
Additional Resources
Calcitriol (active form of vitamin D, e.g. Rocaltrol)
Glossary
acc1
acc item1
fasdf
p1
replace
Container
Med1
Dose
CI
Precaution
Comment
repalce when HF
hide when cancer
acc no 1
Med 1
Dose
CI
Precaution
Comment
replace when HF
Hide when Cancer
Shared Care Planning
Supportive Care
Health Condition
Chronic Disease
Preferences
Health Plan
Healthcare Team
Advance Care Planning or ACP
Personal Directive
Enduring Power Attorney
Goals of Care (Designation) or GoC
“Greensleeve”
Palliative care
End of Life Care
Accordion Container
Additional Resources
What is Palliative Care?
Accordion Container
Darbepoetin starting dose when Hgb < 95 g/L and iron replete.
Darbepoetin adjustment schedule if Hgb BELOW target:
Darbepoetin adjustment schedule if Hgb ABOVE target or rising significantly:
Dose Adjustment Schedule for epoetin alpha (Eprex ®)
Glossary
Symptom and Medical Management
Patient Handouts
Maintenance: Calcium Dosing Guideline
Additional Resources
What is End of Life Care?
Helpful Links
References
Helpful Links
References
References
Helpful Links
References
Additional Resources
References
Additional Resources
References
Additional Resources
References
Hide for non liver or kidney
Not indicated except in liver
Step 1: Continue Goals of Care Discussions
References
Hide for HF
except HF
General
General
General
General
General
Restless Legs
Lack of Appetite
Depression & Anxiety
Fatigue
Muscle Cramps
Numbness & Tingling
Taste Changes
Diarrhea
Dehydration
Itchiness
Swelling
Difficulty Swallowing
Sleep Problems
Palliative Care
Accordion Container
What causes restless leg syndrome
What you can do to help manage your restless leg syndrome
When you should talk to your healthcare team
Accordion Container
What causes a lack of appetite
What you can do to help manage your lack of appetite
When you should talk to your healthcare team
Accordion container
What causes depression & anxiety
What you can do to help manage your depression & anxiety
When you should talk to your healthcare team
Accordion container
What causes fatigue
What you can do to help manage you fatigue
When you should talk to your healthcare team
Accordion container
What causes muscle cramps
What you can do to help manage your muscle cramps
Accordion container
When you should talk to your healthcare team
What causes numbness & tingling
What you can do to help manage your numbness & tingling
When to talk to your healthcare team
Accordion Container
What causes taste changes?
What you can do to help manage your taste changes
When to talk to your healthcare team
Accordion Container
What causes diarrhea?
What you can do to help manage your diarrhea
When to talk to your healthcare team
Accordion Container
What causes dehydration?
What you can do to help manage your dehydration
When to talk to your healthcare team
Accordion Container
What causes itchiness?
What you can do to help manage your itchiness
When to talk to your healthcare team
Accordion Container
What causes swelling?
What you can do to help manage your swelling
When to talk to your healthcare team
Accordion Container
What causes sleep problems?
What you can do to help manage your sleep problems
When to talk to your healthcare team
What causes nausea & vomiting?
Accordion Container
What you can do to help manage your difficulty with swallowing
When to talk to your healthcare team
What causes difficulty in swallowing?
What causes nausea & Vomiting
What causes pain
Accordion Container
what can I expect in the last weeks and days of life?
What will happen if my family & friends can't care for me at home?
Helpful links to learn more about palliative and end of life care in Alberta
Links
Links
Links
Links
Links
Links
Links
Links
Links
Links
Links
Links
Links
Cancer Management
Step 1: Consider the Underlying Causes of Cancer Management
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Advance Care Planning
Palliative & End of Life
Access to Resources
Topical Compounded Products
Dose
CI
Precaution
Comment
Caution
General-Caution
Topical Compounded Products
Dose
CI
Precaution
Comment
General Condition
condition for HF & KD
General CI
Additional Resources
Lemborexant
Dose
CI
Precaution
Comment
Hide for Kidney and Cirrhosis
Hide for Cancer COPD HF
Sertraline
Dose
CI
Precaution
Comment
CI-Genernal
General
CI for Cirrhosis
Living with Heart Failure
Living with COPD
Additional Resources
TargetSectionId
Section 1
News
Events
Section 2
FAQ
Integrated Supportive Care
What is one:carepath?
Who is One:carepath for?
Patient Symptoms
About You & Your Health Conditions
Managing Your Health Condition
Your Shared Care Plan
Your Advance Care Planning
Patient Portal Home Page
Provider Pathway Content
Diease Area Description
Confirm Comorbidities
Hero
Quick Access
Posters
Call to Action
Highlighted Features
Footer
Navbar
Integrated Supportive Care
Home
Interactive Clinical Assessment
Patients
Content
Symptom
Fatigue
STEP 1: IDENTIFY AND TREAT POTENTIAL REVERSIBLE CAUSES
Disease Area (KF)
Anxiety/Depression
Breathlessness
Constipation
Edema
Kidney
COPD
Heart
Liver
Cancer
Fatigue
New General Symptom Management Content - Symptom 1
New Section
Cause 1
Edema
Step 1. General Symptom Management
New Section
Cause 1
Step 4. Palliative Care Consult
Fatigue
New General Symptom Management Content - Symptom 1
New Section
Cause 1
Anxiety/Depression
Step 1: General Symptom Management
New Section
Cause 1
STEP 2: GENERAL Non-Pharmacological
Non-Pharmacological Symptom Nuances
Non-Pharmacological: Disease Specific Symptom Management
Cause 1
STEP 3: Pharmacological
Liver Nuance
Kidney Nuance
Step 4: Palliative Care Consult
Constipation old
STEP 2: Non-Pharmacological Management
STEP 3: Pharmacological Management
STEP 4: Palliative Care Consult
STEP 2: NON-PHARMACOLOGICAL MANAGEMENT
STEP 3: PHARMACOLOGICAL MANAGEMENT
HEART FAILURE
CIRRHOSIS
KIDNEY FAILURE
ABOUT PAIN: GENERAL DESCRIPTION & DEFINITION
STEP 1: IDENTIFY AND TREAT POTENTIAL REVERSIBLE CAUSES
STEP 2: NON-PHARMACOLOGICAL MANAGEMENT
STEP 3: PHARMACOLOGICAL MANAGEMENT
KIDNEY DISEASE - NEUROPATHIC
KIDNEY DISEASE - NOCICEPTIVE
STEP 4: PALLIATIVE CARE CONSULT
PHARMACOLOGICAL PALLIATIVE CARE END OF LIFE NEUROPATHIC PAIN
PHARMACOLOGICAL PALLIATIVE CARE END OF LIFE NOCICEPTIVE PAIN
Superficial pain
Bone
Soft Tissue
Muscle Relaxants
Visceral
Dexamethasone
Bisphosphonate – Clodronate 1600-2400 mg PO daily
Denosumab 120 mg SC every 4 weeks
STEP 4: PALLIATIVE CARE CONSULT Version 2
NSAID (systemic)
NSAID (topical)
Diazepam
Baclofen
Tizanidine
GFR 0-7
GFR 8-15
GFR 15-30
GFR 30+
EFS Severe
EFS Not Severe
Other Assessment Tool
EFS Severe
EFS Not Severe
EFS Severe
EFS Not Severe
Heart Failure
FEV1
FEV2
EFS Severe
EFS Not Severe
Weight
Another Tool
New Measurement Level
Test Disease Area
Fatigue old
STEP 1: Consider the Underlying Causes of Fatigue
STEP 2: Non Pharmacological Management of Fatigue
STEP 3: Pharmacological Management v1 - Modelled after Med Table
STEP 4: Palliative Care Consult
Nausea & Vomiting
Step 1: Consider the Underlying Causes of Nausea & Vomiting
Step 2: Non-Pharmacological Management
STEP 4: Palliative Care Consult
Step 3: Pharmacological Management
Dexamethasone-Append-Cancer
HF-Replace-Buproprion
Step 3: Pharmacological Management v2 - Fewest Nodes - Better management
Dexamethasone-Append-Cancer
STEP 3: Pharmacological Management V3 - Will not work as this does not align with wholistic approach
Heart Failure
Cancer
STEP 3: Pharmacological Management v4 - Most Nodes and Difficult to Manage
Modafinil (Provigil)
Methylphenidate (Ritalin)
Bupropion
Modafinil-<>HF
Methyphenidate <> HF
Modafinil-Cirrhosis-ReduceDose <> HF
KIdney
STEP 3: Pharmacological Management v5 - Using Hide
Dexamethasone
Reduce Dose-Cirrhosis - Need to create nuance to a nuance
Modafinil
Dexamethasone
Methylphenidate (Ritalin)
Reduce Dose Cirrhosis
STEP 3: Pharmacological Management of Fatigue
Bupropion
Methyphenidate & Modafinil
Continue with algorithm
Dexamethasone
Bisacodyl; Peristaltic stimulant
Cancer Adjusted Dose
Methyphenidate & Modafinil
Rule-Hide when HF selected
Bupropion
Rule-Hide when Cirrhosis selected
Psyllium (Metamucil)
Polyethylene glycol (PEG 3350) (LAX-A-DAY); Osmotic laxative
Lactulose or Sorbitol; Osmotic laxative
Sennosides (SenekotÒ); Peristaltic stimulant
Glycerin Suppository
Sodium-phosphate enema (Fleet Enema)
Magnesium citrate or hydroxide or sulfate (Epsom salt)
Methylnaltexone (RelistorÒ); Peripherally acting μ-opioid receptor antagonists (PAMORAs)
Kidney Disease Dose Adjustment
Naloxegol (MovantikÒ); Peripherally acting μ-opioid receptor antagonists (PAMORAs)
KidneyDiseaseDoseAdjustment
CirrhosisChildPughCAvoidUse
Prucalopride; Prokinetics
KidneyDiseaseDoseAdjustment
Manual Disimpaction; for severe constipation
Cholestatic Pruritus
Step 1: Consider the Underlying Causes of Pruritus
Step 2: Non-pharmacological Management
Good Skin Care and Moisturizers
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Is this terminal phase of life? yes
Is this terminal phase of life? no
Topical Treatment
Pramoxine
Capsaicin 0.025% or 0.075% Ointment
Menthol, Camphor and Phenol are separate products that can be added to most creams, typically in the range of 0.3-1.0%
Gamma-Linolenic acid (GLA) 2.2% cream
Systemic Treatment
Doxepin
CI
Precaution
Comment
Cholestyramine
Rifampin
CI
Precaution
Liver Cirrhosis
Naltrexone
CI
Precaution
Comment
Restless Legs
Step 1: Consider the Underlying Causes of Restless Leg Syndrome
Step 2: Consider Non-Pharmacological Management
Step 3: Pharmacological Management
Gabapentin
Dose
CKD Dose
Liver Dose
Pregabalin
Pramipexole (Mirapex)
Rotigotine (Neupro)
CI
Precaution
Comment
CKD, Liver
Dose
CKD
CI
Precaution
Comment
Dose
CI
Precaution
Comment
Dose
CI
Precaution
Comment
Ropinirole (Requip)
Dose
CI
Precaution
Comment
Midazolam (Versed)
Dose
CKD,Cir,CAN,HF
COPD
CI
Precaution
Comment
CKD,HF
COPD
Neuropathic Pain (OLD)
Step 1: Consider the Underlying Causes of Neuropathic Pain
Step 2: Non-Pharmacological Management of Neuropathic Pain
Step 3: Pharmacological Management of Neuropathic Pain
Step 4: Palliative Care Consult
Non-Opioid Treatment
Step 2: Non-Opioid
Opioid Treatment
Acetaminophen
Dose
CI
Precaution
Comment
Diclofenac Gel
Dose
Comment
Hydromorphone
Dose
CI
Precaution
Comment
Fentanyl Transdermal Patch
Dose
CI
Precaution
Comment
Methadone
Dose
CI
Precaution
Comment
Nociceptive Pain (backup -Old)
Step 1: Consider the Underlying Causes of Nociceptive Pain
Step 2: Non-pharmacological Management of Nociceptive Pain
Step 3: Pharmacological Management of Nociceptive Pain
Step 4: Palliative Care Consult
Non-opioids (for mild pain (typically >3/10)
Step 2: Moderate Pain (4-6/10)
Opioids
Step 5: Patient Education & Self-Care
Gabapentin
Dose
CI
Comment
Pregabalin
Dose
CI
Precaution
Comment
Amitriptyline
Dose
CI
Precaution
Comment
Acetaminophen
Dose
CI
Precaution
Comment
Hydromorphone
Dose
CI
Precaution
Comment
Fentanyl Transdermal Patch
Dose
CI
Precaution
Comment
Methadone
Dose
CI
Precaution
Comment
Step 5 Patient Education & Self Care
Step 5: Patient Education and Self Care
When is an opioid indicated?
Precaution
General
General
Fatigue
Step 1: Consider the Underlying Causes of Fatigue
Step 2: Non-pharmacological Management of Fatigue
Step 3: Pharmacological Management of Fatigue
Step 4: Palliative Care Consult
General - Precaution
Methyphenidate
Dose
CI
Precaution
HF
Modafinil
Dose
CI
Precaution
HF
Dexamethasone
Dose
CI
Precaution
Constipation
Step 1: Consider the Underlying Causes of Constipation
Step 2: Non-pharmacological Management of Constipation
Step 3: Pharmacological Management of Constipation
Step 4: Palliative Care Consult
Psyllium Husk
Dose
CI
Comment
General
Precaution
Polyethylene Glycol (PEG 3350)
Dose
CI
Precaution
Comment
Sennosides
Dose
CI
Precaution
Comment
Bisacodyl
Dose
CI
Precaution
Comment
Cancer
Glycerin or Bisacodyl Suppository
Dose
CI
Precaution
Comment
KF
Sodium-phosphate Enema (Fleet Enema)
Dose
CI
Precaution
Magnesium citrate or hydroxide or sulfate (Epsom Salt)
Dose
Precaution
Methylnaltexone
Dose
CI
Precaution
Comment
KF
Cirrhosis
General
Cirrhosis
Secretagogues (Linaclotide)
Prokinetics (Prucalopride)
Liver Renal - Precaution
General - CI
General - CI
General - P
General - CI
General - P
General - CI
General - P
COPD - P
Liver - CI
General
General
Lactulose
Dose
CI
Precaution
Comment
General
General
General
General
General
General
General
General
General
Dose - CKD
General - CI
General - Precaution
General - Precaution
High Mineral Oil Enema
Dose
CI
Precaution
Comment
General - PI
General - CI
Dose - CKD
General - CI
Ducolax Suppository
Dose
CI
Precaution
Comment
General - CI
General - Precaution
Demo Medication
Dose
CI
Precaution
Comment
Alarm When COPD
Warning when Heart Failure
Hide When Cirrhosis
Replace When Kidney Disease
Hide When Cancer
Append When Cancer
Demo Symptom
Step 1: Consider the Underlying Causes of Demo Symptom
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
New Med 1
Dose
CI
Precaution
Comment
General - CI
General - Precaution
CKD - Dose
CKD - Dose
General - CI
General - precaution
Comment - HF
Amitriptyline
Dose
CI
Precaution
Comment
General - CI
General - precaution
Liver - CI
Acetominophen
Dose
CI
Precaution
Comment
General - Precaution
Cirrhosis - CI (HIDE)
Liver - CI
HIDE
NOT HF
General
General
General
General
General
General
HIDE Liver
CI
General
Non-Opioid Treatment - Accordion
General Information
Reference Accordion
References
Opioid Treatment - Accordion
Opioid Considerations
Initiating Opioid Therapy
Opioid Titration
Helpful Links
Pain - Neuropathic
Step 1: Consider the Underlying Causes of Neuropathic Pain
Step 2: Non-Pharmacological Management of Neuropathic Pain
Step 3: Pharmacological Management of Neuropathic Pain
Step 4: Palliative Care Consult
Reference Accordion
Helpful Links
References
2. Non-Opioid Therapy
3. Opioid Therapy
Hydromorphone
Dose
CI
Precaution
Comment
Fentanyl Transdermal Patch
Dose
CI
Precaution
Comment
Methadone
Dose
CI
Precaution
Comment
Opioid Treatment - Accordion
Opioid Considerations
Initiating Opioid Therapy
Opioid Titration
Gabapentin
Dose
CI
Precaution
Comment
Pregabalin
Dose
CI
Precaution
Comment
Amitriptyline
Dose
CI
Precaution
Comment
Acetaminophen
Dose
CI
Precaution
Comment
Non-Opioid Treatment - Accordion
General Information
CKD - Dose
General - Precaution
CKD - Dose
General - precaution
Comment - kidney/liver
General - CI
General - precaution
General - Precaution
General
General
General
Comment - HF
CKD/Cirrhosis
Special Considerations for Opioid Induced Constipation (OIC)
Dose - Cirrhosis
Peripherally acting μ-opioid receptor antagonists (PAMORAS)
HF/CKD Hide
Methadone (2)
Diclofenac Gel
Dose
CI
Precaution
Comment
Kidney/Cirrhosis
Precaution - Kidney Failure
Morphine (immediate release)
Dose
CI
Precaution
Comment
General
CI - Cirrhosis
Buprenorphine
Dose
CI
Precaution
Comment
Oxycodone
Dose
CI
Precaution
Comment
Cirrhosis/Kidney
CI - Cirrhosis
Comment - Kidney/Liver
Kidney CI
Dose - Cirrhosis
Comment - kidney/liver
Precaution - HF
Cirrhosis - dose
General - comment
CI - liver/hepatic encephalopathy
Carbamazepine
Dose
CI
Precaution
Comment
General - CI
CI - Cirrhosis/HF
General - Precaution
Dose adjust - CKD/Cirrhosis
General Comment
Doxepin
Dose
CI
Precaution
Comment
General - CI
CI - HF/Cirrhosis
General - CI
1. Start with Adjuvant Therapy
Pain - Nociceptive
Step 1: Consider the Underlying Causes of Nociceptive Pain
Step 2: Non-pharmacological Management of Nociceptive Pain
Step 3: Pharmacological Management of Nociceptive Pain
Step 4: Palliative Care Consult
First Line Therapy (Bulk Forming Laxatives)
First Line Therapy (Osmotic Laxatives)
First Line Therapy (Stimulant Laxatives)
Second Line Therapy (Suppositories)
Third Line Therapy (Alternative Treatments)
Fourth Line Therapy (Special Considerations) - Specialist referral recommended
Comment
Contraindication
Comment
General
Non-Opioid Therapy
Acetaminophen
Dose
CI
Precaution
Comment
Cirrhosis - CI (HIDE)
Diclofenac Gel
Dose
CI
Precaution
Comment
Non-Opioid Treatment - Accordion
Opioid Therapy
Hydromorphone
Dose
CI
Precaution
Comment
Kidney/Cirrhosis
Fentanyl Transdermal Patch
Dose
CI
Precaution
Comment
Precaution - Kidney Failure
Morphine (immediate release)
Dose
CI
Precaution
Comment
CI - Cirrhosis
Hide - Kidney
Buprenorphine
Dose
CI
Precaution
Comment
Oxycodone
Dose
CI
Precaution
Comment
Cirrhosis/Kidney
CI - Cirrhosis
Comment - Kidney/Liver
Methadone
Dose
CI
Precaution
Comment
Opioid Treatment - Accordion
Opioid Considerations
Initiating Opioid Therapy
Opioid Titration
CI - Liver
General - CI
Disclaimer
Anorexia
Step 1: Consider the Underlying Causes of Anorexia
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Delirium
Step 1: Consider the Underlying Causes of Delirium
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Depression
Step 1: Consider the Underlying Causes of Depression
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Diarrhea
Step 1: Consider the Underlying Causes of Diarrhea
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Edema
Step 1: Consider the Underlying Causes of Edema
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Numbness/Tingling
Step 1: Consider the Underlying Causes of Numbness & Tingling
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Shortness of Breath
Step 1: Consider the Underlying Causes of Shortness of Breath
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Bupropion
Dose
CI
Precaution
Comment
General
General
General
General
General
General
General
General
Sleep Disturbance
Step 1: Consider the Underlying Causes of Sleep Disturbance
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Helpful Links
End of Life Care
Step 1: General Principles of End of Life Care
Step 2: Non-pharmacological Management
Step 3: Medical Management
Step 4: Palliative Care Consult
Pregabalin
Dose
CI
Precaution
Comment
DEMO Symptom - Line of Treatment
Step 1: Consider the Underlying Causes of DEMO Symptom - Line of Treatment
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Pregabalin (2)
Dose
CI
Precaution
Comment
HIDE for kidney/liver
Pregabalin (1)
Dose
CI
Precaution
Comment
Kidney
Liver
Helpful Links
References
Med 2
Dose
CI
Precaution
Comment
HF
Hide HF
How to use onecarepath
Second Line Therapy (Stimulants)
Bisacodyl
Dose
CI
Precaution
Comment
Cancer - Dose
General - CI
General
COPD Description
Heart Failure Description
Cirrhosis Description
Advanced Chronic Kidney Disease Description
Cancer Description
Mild Symptoms: limited evidence exists for most medications
test2
Step 4: Palliative Care Specialist Consultation
Terminal Care Considerations
If pain persists add a non-opioid +/- adjuvant therapy
If pain persists consider adding an opioid, +/- adjuvant, +/- non-opioid
End of Life Care
Melatonin
Dose
CI
Precaution
Comment
Mirtazapine
Dose
CI
Precaution
Comment
Trazodone
Dose
CI
Comment
Doxepin
Dose
Precaution
Comment
Moderate to severe symptoms
Zopiclone
Dose
CI
Precaution
Comment
Gabapentin
Dose
CI
Precaution
Comment
Pregabalin
Dose
CI
Precaution
Comment
Precaution - HF
Dose Adjustment - CKD
Dose Adjustment - Cirrhosis
Comment - Kidney/Liver
CI - Liver HE
Dose adjust - Kidney
Dose Adjust - Liver
comment - kidney/liver
Precaution
General CI
Fentanyl Transdermal Patch
Liver - MasterHide
Liver CI
Acetaminophen
Liver CI - MasterHide
Pain - Neuropathic
Pain - Nociceptive
Restless Legs
Constipation
Dose
CI
Precaution
Comment
Dose
CI
Precaution
Comment
med 1 for step 7
Dose
CI
Precaution
Comment
Fatigue
Shortness of Breath
Morphine
Carbamazepine
Liver Heart - MasterHide
Kidney - MasterHide
Liver CI
Doxepin
Dose
CI
Precaution
Comment
Liver Heart - MasterHide
Acetaminophen
Dose
CI
Precaution
Comment
Liver - MasterHide
Fentanyl Transdermal Patch
Dose
CI
Precaution
Comment
Liver-MasterHide
Morphine
Dose
CI
Precaution
Comment
Kidney - MasterHide
Sodium-phosphate Enema (Fleet Enema)
Dose
CI
Precaution
Comment
Kidney_Heart Failure - MasterHide
Methylphenidate
Dose
CI
Precaution
Comment
Modafinil
Dose
CI
Precaution
Comment
Heart Failure - MasterHide
Heart Failure - MasterHide
Doxepin
Dose
CI
Precaution
Comment
Heart Liver - MasterHide
HF Liver - Hide
Helpful Links
References
Helpful Links
References
Metoclopramide
Dose
CI
Precaution
Comment
General
Kidney precaution
Kidney/Liver Dose
General
Domperidone
Dose
CI
Precaution
Comment
Liver dose adjustment
General
Liver CI
General
Haloperidol
Dose
Precaution
Kidney Dose
Liver Dose
General
Kidney Precaution
Contraindications
Comment
General
Dimenhydrinate
Dose
CI
Precaution
Comment
General
General
General
Haloperidol
Dose
CI
Precaution
Comment
General CI
General
Methotrimeprazine
Liver-MasterHide
Ondansetron
Dose
CI
Precaution
Comment
Kidney Dose Adjustment
Liver Dose Adjustment
General
Liver Precaution
Olanzapine
Dose
CI
Precaution
Comment
General
Kidney CI
General
CINV treatment only
Dose
CI
Precaution
Comment
Dexamethasone
Dose
CI
Precaution
Comment
all conditions except cancer CI
Dexamethasone
Dose
All conditions except cancer - MasterHide
Precaution
Comment
Patient Pathway
Provider Pathway
Medication MasterHide
Patient Pathway
What is One:carepath
Provider Resources
Other
FAQ
About one:carepath
Useful Links
Useful Contacts
Events & Newsletters
Disclaimer & Privacy
Quality Improvement
Quality Improvement
KPI's
Glossary
Choosing Supportive Care
Provider Pathway
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About the Provider Pathway
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Dose 1
Confirm Comorbidities and Risk Stratify
Engage Specialty Care
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Healthcare Providers
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Prepare for Conversations About Your Wishes & Needs
Manage Your Health Conditions
Action Plans
Provider Checklists
Clinical Pathways
Complimentary Treatments
Helpful Links
References
Lidocaine 2.5% cream
Gabapentin
Dose
CI
Precaution
Comment
CI Cirrhosis
Renal + Liver Precaution
Pregabalin
Dose
Comment
ESKD Dose Adjust
ESKD Dose Adjust
Hide (cirrhosis med only)
CI
Precaution
Comment
Cirrhosis CI
CI
Precaution
General Precaution
Comment
general Comment
Liver - CI
General - CI
General
General
Renal
Not indicated except for liver
Renal
CI
General
Renal
Renal
General
General
Renal Dose
COPD Dose
General
General
Liver Dose
Cirrhosis Dose
CI
Liver + Renal CI
Precautions
Liver + Renal
Dose
Renal + Liver CI
Liver + Renal Precaution
Liver CI
Cirrhosis precaution
hide for non liver or kidney
hide for non liver or kidney
hide for non-liver or kidney
Helpful Links
References
Liver CI
HF Precaution
General
Liver Dose
General
Liver CI
CKD, Liver
Ascites
Step 1: Initial Workup
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Hepatic Encephalopathy
Step 1: Consider the Underlying Causes of Hepatic Encephalopathy
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Hepatocellular Carcinoma
Step 1: Consider the Underlying Causes of Hepatocellular Carcinoma
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
What is Worrying you right now?
Your Health Conditions
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Your Wishes and Preferences
Symptom Management Guides
Your Health Plan
What is Shared Care Planning?
Steps in Shared Care Planning
What is Advance Care Planning?
Your Green Sleeve
Preparing for the Final Weeks & Days of Life
Your Shared Care Plan
Basic fluid workup (for patients who have had a thorough fluid analysis before):
Extended ascites fluid workup (for patient having a first-tine paracentesis):
Mild Ascites
Spironolactone Monotherapy
Dose
CI
Precaution
Comment
General Precaution
Amiloride (Substitute for Spironolactone)
Dose
CI
Precaution
Comment
Mild to Moderate Ascites
Tense Ascites
Lactulose (oral)
Dose
CI
Precaution
Comment
If oral intake safe/tolerated
If oral intake not safe/not tolerated
Lactulose (nasogastric)
If improvement start secondary prophylaxis
Secondary Prophylaxis
Dose
CI
Precaution
Comment
If no improvement
Rifaximin
Dose
CI
Precaution
Comment
Patient Symptom - Pain
Step 1: Consider the Underlying Causes of Patient Symptom - Pain
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Patient Symptom - Pain
Step 1: What can I try at home?
Step 2: What treatment choices do I have?
Step 3: Pharmacological Management
Step 4: Pain Resources
Tailored Outputs Based on Conditions
Confirm Comorbidities
End Of Life Guideline
End of Life
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
CKD Associated Pruritus
Step 1: Consider the Underlying Causes of CKD Associated Pruritus
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Good Skin Care
Complimentary Treatments
Topical Treatment
Systemic Treatment
Pramoxine
Dose
CI
Precaution
Comment
Capsaicin 0.025% or 0.075% Ointment
Dose
CI
Precaution
Comment
Menthol, Camphor and Phenol are separate products that can be added to most creams, typically in the range of 0.3-1.0%
Dose
CI
Precaution
Comment
Gamma-Linolenic acid (GLA) 2.2% cream
Dose
CI
Precaution
Comment
Lidocaine 2.5% cream
Dose
CI
Precaution
Comment
Dose
CI
Precaution
Comment
Pregabalin
Dose
CI
Precaution
Comment
Gabapentin
Dose
CI
Precaution
Comment
ESKD Dose Adjustment
Cirrhosis Dose
Liver & Renal CI
Liver & Renal
ESKD Dose
Liver Dose
Risk Staging
Self-Management & Lifestyle Modifications: General
Establish Community Support & Referrals
Advance Care Planning
Palliative Care
Final Weeks and Days of Life
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
Message
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
Dosing for Combination Diuretics
Dose
CI
Precaution
Comment
Large-volume (≥ 5L) paracentesis AND start combination diuretics if no contraindications
Dose
CI
Precaution
Comment
Diagnostic Criteria for Refractory Ascites & Management
Monitoring for Patients on Diuretics
How to titrate up diuretics
References
Additional Resources
COPD
Step 1: COPD Management
Step 2: Pharmacological Management
Heart Failure Management
Step 1: Consider the Underlying Causes of Heart Failure Management
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 3: Exacerbation Management
Dose
CI
Precaution
Comment
Dose
CI
Precaution
Comment
Examples of converting oral to subcutaneous administration
When to Consult a Palliative Care Specialist
EMS Palliative and End of Life Care Assess, Treat, and Refer (EMS PEOLC ATR) Initiative
Services required for caring for patients at home, location of care and location of death
Step 5: What Happens After Death?
Symptom Management Near the End of Life
Pain
Breathlessness
Fluid Management
Respiratory Secretions
Constipation
Fatigue & Sleep Disturbance
Restless Legs Syndrome
Delirium & Agitation
Poor Appetite & Intake
Muscle Cramps
Helpful Links
Shared Care Plan
COPD
Heart Failure
Cirrhosis
Advanced CKD
Cancer
Muscle Cramps
Step 1: Consider the Underlying Causes of Muscle Cramps
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Symptom Management
Medical Management
General
Smoking
Immunization
Nutrition
Exercise
Social Determinants of Health
Home Care
Advance Care Planning
Salt Intake
Fluid Intake
Alcohol
Obesity Counselling
Mood and Stress Management
Resources
Pulmonary Rehabilitation
Calgary COPD and Asthma Program (CCAP)
Alberta Healthy Living Program
Community Paramedics (CP)
Home Care (COPD homecare specific teams)
Alberta Quits
Other Resources
Your Support Team
Palliative & End of Life Care
Symptom Management for Advanced CKD
Constipation
What causes constipation?
What you can do to help manage your constipation
When you should talk to your healthcare provider
Medication 1
Dose
CI
Precaution
Comment
Mona
Step 1: Consider the Underlying Causes of Mona
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Medication 1
Dose
CI
Precaution
Comment
CKD
Acidosis Guideline
Acidosis (Metabolic) - Clinical Algorithm
Dosing Chart for Sodium Bicarbonate
Additional Resources:
Blood Pressure Guideline
Additional Resources
Sodium/Fluid Statement
Sodium Intake
Fluid Intake
Rehydration if patients are not able to drink orally
Considerations at End of Life
Nausea & Vomiting
Accordion Container
What you can do to help manage nausea & vomiting?
When you should talk to my healthcare team?
Links
Accordion Container
Links
Pain
Accordion Container
What you can do to help manage your pain
When you should talk to your healthcare team
Links
Shortness of Breath
Accordion Container
What causes shortness of breath
What you can do to help manage shortness of breath
When you should talk to your healthcare team
Links
Anemia Guideline
Iron Protocol for Conservatively Managed Patients
HGB/ESA Protocol & Dose Adjustment Schedule for darbepoietin (Aranesp®)
Additional Resources
Calcium/Phosphorus Guideline
Dose Adjustment Guideline for Phosphate Binders – Recommended Initial Calcium Dosing
Dose Adjustment Guideline for Non-Calcium Based Phosphate Binders (may be used alone or as an adjuvant therapy)
High Calcium Clinical Guideline
Lipids Guideline
Additional Resources
Potassium Guideline
Potassium - Clinical Algorithm
Additional Resources
Vitamin D Statement
Considerations at End of Life:
Additional Resources
Calcitriol (active form of vitamin D, e.g. Rocaltrol)
Glossary
acc1
acc item1
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p1
replace
Container
Med1
Dose
CI
Precaution
Comment
repalce when HF
hide when cancer
acc no 1
Med 1
Dose
CI
Precaution
Comment
replace when HF
Hide when Cancer
Shared Care Planning
Supportive Care
Health Condition
Chronic Disease
Preferences
Health Plan
Healthcare Team
Advance Care Planning or ACP
Personal Directive
Enduring Power Attorney
Goals of Care (Designation) or GoC
“Greensleeve”
Palliative care
End of Life Care
Accordion Container
Additional Resources
What is Palliative Care?
Accordion Container
Darbepoetin starting dose when Hgb < 95 g/L and iron replete.
Darbepoetin adjustment schedule if Hgb BELOW target:
Darbepoetin adjustment schedule if Hgb ABOVE target or rising significantly:
Dose Adjustment Schedule for epoetin alpha (Eprex ®)
Glossary
Symptom and Medical Management
Patient Handouts
Maintenance: Calcium Dosing Guideline
Additional Resources
What is End of Life Care?
Helpful Links
References
Helpful Links
References
References
Helpful Links
References
Additional Resources
References
Additional Resources
References
Additional Resources
References
Hide for non liver or kidney
Not indicated except in liver
Step 1: Continue Goals of Care Discussions
References
Hide for HF
except HF
General
General
General
General
General
Restless Legs
Lack of Appetite
Depression & Anxiety
Fatigue
Muscle Cramps
Numbness & Tingling
Taste Changes
Diarrhea
Dehydration
Itchiness
Swelling
Difficulty Swallowing
Sleep Problems
Palliative Care
Accordion Container
What causes restless leg syndrome
What you can do to help manage your restless leg syndrome
When you should talk to your healthcare team
Accordion Container
What causes a lack of appetite
What you can do to help manage your lack of appetite
When you should talk to your healthcare team
Accordion container
What causes depression & anxiety
What you can do to help manage your depression & anxiety
When you should talk to your healthcare team
Accordion container
What causes fatigue
What you can do to help manage you fatigue
When you should talk to your healthcare team
Accordion container
What causes muscle cramps
What you can do to help manage your muscle cramps
Accordion container
When you should talk to your healthcare team
What causes numbness & tingling
What you can do to help manage your numbness & tingling
When to talk to your healthcare team
Accordion Container
What causes taste changes?
What you can do to help manage your taste changes
When to talk to your healthcare team
Accordion Container
What causes diarrhea?
What you can do to help manage your diarrhea
When to talk to your healthcare team
Accordion Container
What causes dehydration?
What you can do to help manage your dehydration
When to talk to your healthcare team
Accordion Container
What causes itchiness?
What you can do to help manage your itchiness
When to talk to your healthcare team
Accordion Container
What causes swelling?
What you can do to help manage your swelling
When to talk to your healthcare team
Accordion Container
What causes sleep problems?
What you can do to help manage your sleep problems
When to talk to your healthcare team
What causes nausea & vomiting?
Accordion Container
What you can do to help manage your difficulty with swallowing
When to talk to your healthcare team
What causes difficulty in swallowing?
What causes nausea & Vomiting
What causes pain
Accordion Container
what can I expect in the last weeks and days of life?
What will happen if my family & friends can't care for me at home?
Helpful links to learn more about palliative and end of life care in Alberta
Links
Links
Links
Links
Links
Links
Links
Links
Links
Links
Links
Links
Links
Cancer Management
Step 1: Consider the Underlying Causes of Cancer Management
Step 2: Non-pharmacological Management
Step 3: Pharmacological Management
Step 4: Palliative Care Consult
Advance Care Planning
Palliative & End of Life
Access to Resources
Topical Compounded Products
Dose
CI
Precaution
Comment
Caution
General-Caution
Topical Compounded Products
Dose
CI
Precaution
Comment
General Condition
condition for HF & KD
General CI
Additional Resources
Lemborexant
Dose
CI
Precaution
Comment
Hide for Kidney and Cirrhosis
Hide for Cancer COPD HF
Sertraline
Dose
CI
Precaution
Comment
CI-Genernal
General
CI for Cirrhosis
Living with Heart Failure
Living with COPD
Additional Resources
Actoin
Replace
Append Warning
Append Alarm
Append Note
Hide